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Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载：282/0  |  提交时间：2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：113/15  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Cloning and Functional Characterization of a Squalene Synthase from Paris polyphylla var. yunnanensis 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 7
作者:  Gao,Jian-Xiong;  Chen,Yue-Gui;  Li,De-Sen;  Lin,Liang;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(5087Kb)  |  收藏  |  浏览/下载：152/37  |  提交时间：2022/04/02
Paris polyphylla var  Yunnanensis  squalene synthase  steroidal saponins  squalene  in vitro enzymatic assay  MOLECULAR-CLONING  SAPONINS  EXPRESSION  GENE  GLYCOSIDES  PLANTS  SQS  
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
作者:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(2409Kb)  |  收藏  |  浏览/下载：106/29  |  提交时间：2022/04/02
terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Effect of CYP3A4 on liver injury induced by triptolide 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020
作者:  Xiao, Xuerong;  Zhang, Ting;  Huang, Jianfeng;  Zhao, Qi;  Li, Fei
浏览  |  Adobe PDF(4498Kb)  |  收藏  |  浏览/下载：128/42  |  提交时间：2021/01/05
Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events 期刊论文
PHARMACOLOGICAL RESEARCH, 2020
作者:  Huang, Jian-Feng;  Zhao, Qi;  Dai, Man-Yun;  Xiao, Xue-Rong;  Zhang, Ting;  Zhu, Wei-Feng;  Li, Fei
浏览  |  Adobe PDF(3869Kb)  |  收藏  |  浏览/下载：150/37  |  提交时间：2021/01/05
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：289/152  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：219/27  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Community Structures and Antifungal Activity of Root-Associated Endophytic Actinobacteria of Healthy and Diseased Soybean 期刊论文
MICROORGANISMS, 2019, 卷号: 7, 期号: 8, 页码: 15
作者:  Liu, Chongxi;  Zhuang, Xiaoxin;  Yu, Zhiyin;  Wang, Zhiyan;  Wang, Yongjiang;  Guo, Xiaowei;  Xiang, Wensheng;  Huang, Shengxiong
浏览  |  Adobe PDF(1295Kb)  |  收藏  |  浏览/下载：229/49  |  提交时间：2019/10/28
Sclerotinia sclerotiorum (Lib  ) de Bary  diseased soybean root  antifungal activity  actinobacterial community  new agroactive compounds  
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载：246/41  |  提交时间：2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol