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Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：277/42  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：184/37  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载：464/203  |  提交时间：2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
浏览  |  Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：802/149  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Melodinine V, an antitumor bisindole alkaloid with selective cytotoxicity from Melodinus henryi 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 20, 页码: 4895-4898
作者:  Liu, Ya-Ping;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Feng, Tao;  Zhao, Yun-Li;  Li, Yan;  Lau, Clara Bik-San;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1084Kb)  |  收藏  |  浏览/下载：273/88  |  提交时间：2017/01/05
Melodinine v  Bisindole  Inhibited Cell Proliferation  Cell Cycle Arrest  Cellular Apoptosis  Ht-29 Cells  
Amides and neolignans from the aerial parts of Piper bonii 期刊论文
PHYTOCHEMISTRY, 2016, 卷号: 129, 期号: 1, 页码: 36-44
作者:  Ding, Duo-Duo;  Wang, Yue-Hu;  Chen, Ya-Hui;  Mei, Ren-Qiang;  Yang, Jun;  Luo, Ji-Feng;  Li, Yan;  Long, Chun-Lin;  Kong, Yi
浏览  |  Adobe PDF(612Kb)  |  收藏  |  浏览/下载：276/72  |  提交时间：2016/11/04
Piper Bonii  Piperaceae  Amides Neolignans  Antiplatelet  
Four New Minor Compounds from Seeds of Plantago asiatica 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2016, 卷号: 11, 期号: 5, 页码: 667-670
作者:  Gao, Zhonghua;  Zhang, Ling;  Kong, Lingmei;  Yang, Yan;  Pu, Debing;  Gao, Junbo;  Shang, Shanzhai;  Li, Yan;  Xiao, Weilie
浏览  |  Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：218/34  |  提交时间：2016/08/22
Plantago Asiatica  Dibenzylbutane Lignan  Acetylenic Glycoside  Indole Alkaloid  Ionone Derivative  
Three new monoterpenoid indole alkaloids from Vinca major 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2016, 卷号: 18, 期号: 4, 页码: 328-333
作者:  Zhang, Zhi-Jun;  Du, Ru-Nan;  He, Juan;  Wu, Xing-De;  Li, Yan;  Li, Rong-Tao;  Zhao, Qin-Shi
Adobe PDF(822Kb)  |  收藏  |  浏览/下载：260/73  |  提交时间：2016/08/22
Apocynaceae  Vinca Major  Monoterpenoid Indole Alkaloid  Cytotoxicity  
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
Adobe PDF(7290Kb)  |  收藏  |  浏览/下载：252/54  |  提交时间：2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
Vinmajorines C-E, Monoterpenoid Indole Alkaloids from Vinca major 期刊论文
HELVETICA CHIMICA ACTA, 2016, 卷号: 99, 期号: 2, 页码: 157-160
作者:  Zhang, Zhi-Jun;  Du, Ru-Nan;  He, Juan;  Wu, Xing-De;  Li, Yan;  Li, Rong-Tao;  Zhao, Qin-Shi
Adobe PDF(323Kb)  |  收藏  |  浏览/下载：363/75  |  提交时间：2016/06/27
Vinca Major  Monoterpenoid Indole Alkaloid  Vinmajorines C-e  Cytotoxic Activity