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Amides and neolignans from the aerial parts of Piper bonii
Ding, Duo-Duo; Wang, Yue-Hu; Chen, Ya-Hui; Mei, Ren-Qiang; Yang, Jun; Luo, Ji-Feng; Li, Yan; Long, Chun-Lin; Kong, Yi
2016-09-01
Source PublicationPHYTOCHEMISTRY
Volume129Issue:1Pages:36-44
AbstractSix amides, piperbonamides A-F, three neolignans piperbonins A-C, and 11 known compounds were isolated from the aerial parts of Piper bond (Piperaceae). The structures of piperbonamides A F and piperbonins A-C were elucidated based on the analysis of 1D and 2D NMR and MS data. Piperbonin A, (+)-trans-acuminatin, (+)-cis-acuminatin, (+)-kadsurenone, and pipernonaline showed weak activity against platelet aggregation with IC50 values of 118.2, 108.5, 90.02, 107.3, and 116.3 mu M, respectively, as compared with the positive control, tirofiban, with an IC50 value of 5.24 mu M. Piperbonamides A F were inactive against five tumor cell lines at concentrations up to 40 mu M. (C) 2016 Published by Elsevier Ltd.
KeywordPiper Bonii Piperaceae Amides Neolignans Antiplatelet
DOI10.1016/j.phytochem.2016.07.004
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Plant Sciences
WOS SubjectBiochemistry & Molecular Biology ; Plant Sciences
WOS IDWOS:000381832900004
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/28585
Collection资源植物与生物技术所级重点实验室
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GB/T 7714
Ding, Duo-Duo,Wang, Yue-Hu,Chen, Ya-Hui,et al. Amides and neolignans from the aerial parts of Piper bonii[J]. PHYTOCHEMISTRY,2016,129(1):36-44.
APA Ding, Duo-Duo.,Wang, Yue-Hu.,Chen, Ya-Hui.,Mei, Ren-Qiang.,Yang, Jun.,...&Kong, Yi.(2016).Amides and neolignans from the aerial parts of Piper bonii.PHYTOCHEMISTRY,129(1),36-44.
MLA Ding, Duo-Duo,et al."Amides and neolignans from the aerial parts of Piper bonii".PHYTOCHEMISTRY 129.1(2016):36-44.
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