Amides and neolignans from the aerial parts of Piper bonii
Ding, Duo-Duo; Wang, Yue-Hu; Chen, Ya-Hui; Mei, Ren-Qiang; Yang, Jun; Luo, Ji-Feng; Li, Yan; Long, Chun-Lin; Kong, Yi
2016-09-01
发表期刊PHYTOCHEMISTRY
卷号129期号:1页码:36-44
摘要Six amides, piperbonamides A-F, three neolignans piperbonins A-C, and 11 known compounds were isolated from the aerial parts of Piper bond (Piperaceae). The structures of piperbonamides A F and piperbonins A-C were elucidated based on the analysis of 1D and 2D NMR and MS data. Piperbonin A, (+)-trans-acuminatin, (+)-cis-acuminatin, (+)-kadsurenone, and pipernonaline showed weak activity against platelet aggregation with IC50 values of 118.2, 108.5, 90.02, 107.3, and 116.3 mu M, respectively, as compared with the positive control, tirofiban, with an IC50 value of 5.24 mu M. Piperbonamides A F were inactive against five tumor cell lines at concentrations up to 40 mu M. (C) 2016 Published by Elsevier Ltd.
关键词Piper Bonii Piperaceae Amides Neolignans Antiplatelet
DOI10.1016/j.phytochem.2016.07.004
收录类别SCI
语种英语
WOS记录号WOS:000381832900004
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/28585
专题资源植物与生物技术所级重点实验室
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GB/T 7714
Ding, Duo-Duo,Wang, Yue-Hu,Chen, Ya-Hui,et al. Amides and neolignans from the aerial parts of Piper bonii[J]. PHYTOCHEMISTRY,2016,129(1):36-44.
APA Ding, Duo-Duo.,Wang, Yue-Hu.,Chen, Ya-Hui.,Mei, Ren-Qiang.,Yang, Jun.,...&Kong, Yi.(2016).Amides and neolignans from the aerial parts of Piper bonii.PHYTOCHEMISTRY,129(1),36-44.
MLA Ding, Duo-Duo,et al."Amides and neolignans from the aerial parts of Piper bonii".PHYTOCHEMISTRY 129.1(2016):36-44.
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