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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：2/1  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Antimelanogenic Effect of Isoquinoline Alkaloids from Plumula Nelumbinis 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 43, 页码: 16090-16101
作者:  Chen,Yi-Chi;  Liu,Yang-Yang;  Chen,Liqiang;  Tang,Dong-Mei;  Zhao,Yunli;  Luo,Xiao-Dong
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Plumula Nelumbinis  melanin  tyrosinase  melanogenesis  hyperpigmentation  CHEMICAL-COMPOSITION  DOWN-REGULATION  LOTUS  ANTIOXIDANT  MELANOGENESIS  FLAVONOIDS  OXIDATION  EMBRYO  
Steroidal alkaloids from the roots of Veratrum stenophyllum 期刊论文
FITOTERAPIA, 2023, 卷号: 166, 页码: 105464
作者:  Zhou,Zhong-Shun;  Liu,Yang -Yang;  Zhu,Yan-Yan;  Hu,Bin-Yuan;  He,Ying-Jie;  Luo,XiaoDong
浏览  |  Adobe PDF(1511Kb)  |  收藏  |  浏览/下载：1/1  |  提交时间：2024/07/25
Steroidal alkaloids  Veratrum stenophyllum  Cytotoxic bioactivity  ANTITUMOR-ACTIVITY  RHIZOMES  DNA  
Antifungal alkaloids from Mahonia fortunei against pathogens of postharvest fruit. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 10-10
作者:  Wang, Xiao-Na;  Wang, Zhao-Jie;  Zhao, Yun;  Wang, Huan;  Xiang, Mei-Ling;  Liu, Yang-Yang;  Zhao, Li-Xing;  Luo, Xiao-Dong
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Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
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Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking 期刊论文
FRONTIERS IN VETERINARY SCIENCE, 2021, 卷号: 7, 页码: 615915
作者:  Zheng,Fenshuang;  Zhang,Min;  Yang,Xingwei;  Wu,Feilong;  Wang,Gan;  Feng,Xingxing;  Ombati,Rose;  Zuo,Ruiling;  Yang,Canju;  Liu,Jun;  Lai,Ren;  Luo,Xiaodong;  Long,Chengbo
收藏  |  浏览/下载：113/0  |  提交时间：2022/04/02
leech  blood-sucking  prostaglandin E1  anticoagulant  Haemadipsa sylvestris  MEDICINAL LEECH  PGE1  INFLAMMATION  THERAPY  PAIN  E-1  
Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 6, 页码: 651-658
作者:  Zhang,Ruo-Song;  Liu,Yang-Yang;  Zhu,Pei-Feng;  Jin,Qiong;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1291Kb)  |  收藏  |  浏览/下载：119/44  |  提交时间：2022/04/02
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
作者:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2113Kb)  |  收藏  |  浏览/下载：122/37  |  提交时间：2022/04/02
Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
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Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：168/86  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2