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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
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UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
A clue to the evolutionary history of modern East Asian flora: Insights from phylogeography and diterpenoid alkaloid distribution pattern of the Spiraea japonica complex 期刊论文
MOLECULAR PHYLOGENETICS AND EVOLUTION, 2023, 卷号: 184, 页码: 107772
作者:  Luo,Dong;  Song,Min-shu;  Xu,Bo;  Zhang,Yu;  Zhang,Jian-wen;  Ma,Xiang-guang;  Hao,Xiao jiang;  Sun,Hang
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ampliative Spiraea japonica complex  East Asian flora  Transition belt  Phylogeography  Diterpenoid alkaloids  MOLECULAR PHYLOGEOGRAPHY  SECONDARY METABOLITES  HENGDUAN MOUNTAINS  QUATERNARY CLIMATE  PLANT DIVERSITY  ROSACEAE  DNA  CHLOROPLAST  COALESCENT  CHINA  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
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Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
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euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：133/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Three new jatrophane diterpenoids from Euphorbia peplus Linn. with activity towards autophagic flux 期刊论文
PHYTOCHEMISTRY LETTERS, 2022, 卷号: 50, 页码: 141-146
作者:  Pu, Xue-Xue;  Ran, Xiao-Qian;  Yan, Ying;  Lu, Qing-Yun;  Li, Jin-Cun;  Li, Ying-Yao;  Guan, Shi-Peng;  Cao, Ming-Ming;  Liu, Jie;  Hao, Xiao-Jiang;  Luo, Rong-Can;  Di, Ying-Tong
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INDITTO2 transposon conveys auxin-mediated DRO1 transcription for rice drought avoidance 期刊论文
PLANT CELL AND ENVIRONMENT, 2021, 卷号: 44, 期号: 6, 页码: 1846-1857
作者:  Zhao,Yiting;  Wu,Lixia;  Fu,Qijing;  Wang,Dong;  Li,Jing;  Yao,Baolin;  Yu,Si;  Jiang,Li;  Qian,Jie;  Zhou,Xuan;  Han,Li;  Zhao,Shuanglu;  Ma,Canrong;  Zhang,Yanfang;  Luo,Chongyu;  Dong,Qian;  Li,Saijie;  Zhang,Lina;  Jiang,Xi;  Li,Youchun;  Luo,Hao;  Li,Kuixiu;  Yang,Jing;  Luo,Qiong;  Li,Lichi;  Peng,Sheng;  Huang,Huichuan;  Zuo,Zhili;  Liu,Changning;  Wang,Lei;  Li,Chengyun;  He,Xiahong;  Friml,Jiri;  Du,Yunlong
收藏  |  浏览/下载：84/0  |  提交时间：2022/04/02
DNA transposable elements  indoleacetic acid  Oryza  stress  
Arbuscular mycorrhizal trees influence the latitudinal beta-diversity gradient of tree communities in forests worldwide 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 3137
作者:  Zhong,Yonglin;  Chu,Chengjin;  Myers,Jonathan A.;  Gilbert,Gregory S.;  Lutz,James A.;  Stillhard,Jonas;  Zhu,Kai;  Thompson,Jill;  Baltzer,Jennifer L.;  He,Fangliang;  LaManna,Joseph A.;  Davies,Stuart J.;  Aderson-Teixeira,Kristina J.;  Burslem,David F. R. P.;  Alonso,Alfonso;  Chao,Kuo-Jung;  Wang,Xugao;  Gao,Lianming;  Orwig,David A.;  Yin,Xue;  Sui,Xinghua;  Su,Zhiyao;  Abiem,Iveren;  Bissiengou,Pulcherie;  Bourg,Norm;  Butt,Nathalie;  Cao,Min;  Chang-Yang,Chia-Hao;  Chao,Wei-Chun;  Chapman,Hazel;  Chen,Yu-Yun;  Coomes,David A.;  Cordell,Susan;  de Oliveira,Alexandre A.;  Du,Hu;  Fang,Suqin;  Giardina,Christian P.;  Hao,Zhanqing;  Hector,Andrew;  Hubbell,Stephen P.;  Janik,David;  Jansen,Patrick A.;  Jiang,Mingxi;  Jin,Guangze;  Kenfack,David;  Kral,Kamil;  Larson,Andrew J.;  Li,Buhang;  Li,Xiankun;  Li,Yide;  Lian,Juyu;  Lin,Luxiang;  Liu,Feng;  Liu,Yankun;  Liu,Yu;  Luan,Fuchen;  Luo,Yahuang;  Ma,Keping;  Malhi,Yadvinder;  McMahon,Sean M.;  McShea,William;  Memiaghe,Herve;  Mi,Xiangcheng;  Morecroft,Mike;  Novotny,Vojtech;  O'Brien,Michael J.;  den Ouden,Jan;  Parker,Geoffrey G.;  Qiao,Xiujuan;  Ren,Haibao;  Reynolds,Glen;  Samonil,Pavel;  Sang,Weiguo;  Shen,Guochun;  Shen,Zhiqiang;  Song,Guo-Zhang Michael;  Sun,I-Fang;  Tang,Hui;  Tian,Songyan;  Uowolo,Amanda L.;  Uriarte,Maria;  Wang,Bin;  Wang,Xihua;  Wang,Youshi;  Weiblen,George D.;  Wu,Zhihong;  Xi,Nianxun;  Xiang,Wusheng;  Xu,Han;  Xu,Kun;  Ye,Wanhui;  Yu,Mingjian;  Zeng,Fuping;  Zhang,Minhua;  Zhang,Yingming;  Zhu,Li;  Zimmerman,Jess K.
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NEGATIVE DENSITY-DEPENDENCE  NESTEDNESS  TEMPERATURE  COMPONENTS  TURNOVER  PLANTS  FUNGI  ASSOCIATIONS  ECOLOGY  NETWORK  
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu,Shuai;  Zhang,Cui-Shan;  Ran,Xiao-Qian;  Tang,Xiao-Han;  Guo,Ya-Rong;  Yan,Ying;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rong-Can;  Di,Ying-Tong
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PROMISING BIOLOGICAL-ACTIVITY  LIMONOIDS  CHROMONES  FRUITS  DRUG