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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：100/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：69/15  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker 期刊论文
NATURAL PRODUCT RESEARCH, 2021
作者:  Wang,Yi-ting;  Fan,Shi-rui;  Cai,Jie-yun;  Guo,Jing-jing;  Zhang,Xin-fang;  Yang,Bi-juan;  Hao,Xiao-jiang;  Chen,Duo-zhi
浏览  |  Adobe PDF(375Kb)  |  收藏  |  浏览/下载：63/21  |  提交时间：2022/04/02
Cytotoxic  cycloartane triterpenoid  Aphanamixis polystachya  LEAVES  
Aphananoid A is an Anti-Inflammatory Limonoid with a New 5/6/5 Fused Ring Featuring a C-24 Carbon Skeleton from Aphanamixis polystachya 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2020
作者:  Yang, Bi-Juan;  Fan, Shi-Rui;  Cai, Jie-Yun;  Wang, Yi-Ting;  Jing, Chen-xu;  Guo, Jing-Jing;  Chen, Duo-Zhi;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1960Kb)  |  收藏  |  浏览/下载：112/37  |  提交时间：2021/01/05
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：286/35  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：298/73  |  提交时间：2016/06/27
Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2015, 期号: 4, 页码: 247-250
作者:  Jing, Chen-xu;  Cai, Jie-yun;  Zhang, Yu;  Chen, Duo-zhi;  Hao, Xiao-jiang
浏览  |  Adobe PDF(418Kb)  |  收藏  |  浏览/下载：133/47  |  提交时间：2016/01/19
Phenanthridin  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Limonoids from Aphanamixis polystachya and Their Antifeedant Activity 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 3, 页码: 472-482
作者:  Cai, Jie-Yun;  Chen, Duo-Zhi;  Luo, Shi-Hong;  Kong, Ning-Chuan;  Zhang, Yu;  Di, Ying-Tong;  Zhang, Qiang;  Hua, Juan;  Jing, Shu-Xi;  Li, Shun-Lin;  Li, Sheng-Hong;  Hao, Xiao-Jiang;  He, Hong-Ping
Adobe PDF(477Kb)  |  收藏  |  浏览/下载：386/117  |  提交时间：2014/05/16
Biological-activities  Cipadessa-baccifera  Meliaceae  Tetranortriterpenoids  Sesquiterpenes  Triterpenoids  Prieurianin  Derivatives  Chemistry  Mangrove  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(555Kb)  |  收藏  |  浏览/下载：496/101  |  提交时间：2013/06/08
(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity  
Senegalensions A-C, Three Limonoids from Khaya senegalensis 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2012, 卷号: 7, 期号: 9, 页码: 2024-2027
作者:  Yuan, Chun-Mao;  Zhang, Yu;  Tang, Gui-Hua;  Li, Shun-Lin;  Di, Ying-Tong;  Hou, Li;  Cai, Jie-Yun;  Hua, Hui-Ming;  He, Hong-Ping;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(499Kb)  |  收藏  |  浏览/下载：250/54  |  提交时间：2012/11/30
Biosynthesis  Computational Chemistry  Limonoids  Natural Products  Structure Elucidation