Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker

doi:10.1080/14786419.2021.1906242

KIB OpenIR

	Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker
	Wang,Yi-ting ; Fan,Shi-rui ; Cai,Jie-yun ; Guo,Jing-jing ; Zhang,Xin-fang ; Yang,Bi-juan ; Hao,Xiao-jiang; Chen,Duo-zhi
	2021
Source Publication	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
Abstract	Two new cycloartane triterpenoids, (24 R)-cycloartane-3 beta,24,25,30-tetrol (1) and (24 R)-24,25,30-trihydroxy-9,19-cycloartane-3-one (2), along with three known compounds (3-5) were isolated from leaves and twigs of Aphanamixis polystachya. The new compounds were elucidated based on comprehensive spectroscopic analysis, including 1 D, 2 D NMR and HREIMS. The in vitro cytotoxic activities evaluation of five human cancer cell lines revealed that compound 1 exhibited cytotoxic activity on all of tested human cancer cell lines, while compound 2 only had specific activity on SMMC-7721 cell line.
Keyword	Cytotoxic cycloartane triterpenoid Aphanamixis polystachya LEAVES
DOI	10.1080/14786419.2021.1906242
WOS ID	WOS:000658923000001
Citation statistics
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/73654
Collection	中国科学院昆明植物研究所
Affiliation	1.[Wang, Yi-ting 2.Fan, Shi-rui 3.Cai, Jie-yun 4.Guo, Jing-jing 5.Zhang, Xin-fang 6.Yang, Bi-juan 7.Hao, Xiao-jiang 8.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 9.Yunnan Univ, Dept Chem Sci & Engn, Kunming, Yunnan, Peoples R China 10.Yunnan Tobacco Qual Supervis & Test Stn, Kunming, Yunnan, Peoples R China
Recommended Citation GB/T 7714	Wang,Yi-ting,Fan,Shi-rui,Cai,Jie-yun,et al. Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker[J]. NATURAL PRODUCT RESEARCH,2021.
APA	Wang,Yi-ting.,Fan,Shi-rui.,Cai,Jie-yun.,Guo,Jing-jing.,Zhang,Xin-fang.,...&Chen,Duo-zhi.(2021).Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker.NATURAL PRODUCT RESEARCH.
MLA	Wang,Yi-ting,et al."Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker".NATURAL PRODUCT RESEARCH (2021).

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