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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
Authors:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:199/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  Favorite  |  View/Download:186/1  |  Submit date:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
Authors:  Yan,Xiu-Xiang;  Zhao,Yan-Qiang;  He,Yun;  Disayathanoowat,Terd;  Pandith,Hataichanok;  Inta,Angkhana;  Yang,Li-Xin
View  |  Adobe PDF(3195Kb)  |  Favorite  |  View/Download:23/3  |  Submit date:2024/05/09
Paris polyphylla var  yunnanensis  indigenous medicine knowledge  saponins  cytotoxic effects  pro-apoptotic effects  CELL-CYCLE ARREST  STEROIDAL SAPONINS  HEPATOCELLULAR-CARCINOMA  CHEMICAL-CONSTITUENTS  ASSAY  GLYCOSIDES  LEAVES  GROWTH  STEMS  SITES  
Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity 期刊论文
PHARMACEUTICALS, 2023, 卷号: 16, 期号: 2, 页码: 193
Authors:  Zhang,Xian;  Fan,Yinzhong;  Ye,Ke;  Pan,Xiaoyan;  Ma,Xujun;  Ai,Honglian;  Shi,Baobao;  Liu,Jikai
View  |  Adobe PDF(1718Kb)  |  Favorite  |  View/Download:25/6  |  Submit date:2024/05/09
endophyte fungus  Xylaria curta  cytochalasins  isolation and structure elucidation  cytotoxicity  A-D  METABOLITES  
Structurally Diverse Cytotoxic Polyphenols from Garcinia gracilis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2023, 卷号: 86, 期号: 9, 页码: 2206-2215
Authors:  Ye,Yan-Song;  Duan,Yao-Tao;  Zhou,Zhuo;  Thepkaysone,Khamphanh;  Douangdeuane,Bounleuane;  Xu,Gang
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CAGED XANTHONES  CONSTITUENTS  INHIBITORS  BENZOPHENONES  DERIVATIVES  BIPHENYL  TWIGS  
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
Authors:  Yang,Li-Yuan;  Yi,Ping;  Chen,Jun-Lei;  Li,Yu-Huan;  Qiu,Jue-Lin;  Wang,Zhao-Yang;  Fu,Mao;  Yuan,Chun-Mao;  Huang,Lie-Jun;  Hao,Xiao-Jiang;  Gu,Wei
View  |  Adobe PDF(1860Kb)  |  Favorite  |  View/Download:6/1  |  Submit date:2024/07/10
Primulina eburnea  triterpenes  flavonoids  phenylethanoid glycosides  cytotoxic activity  GLUCOSIDES  LEAVES  CELL  
Design and synthesis of guaianolide-germacranolide heterodimers as novel anticancer agents against hepatocellular carcinoma 期刊论文
DRUG DEVELOPMENT RESEARCH, 2023
Authors:  Yan,Jia-Xin;  Li,Qi-Hao;  Li,Tian-Ze;  Huang,Zhi-Yan;  Ma,Yun-Bao;  Chen,Ji-Jun
View  |  Adobe PDF(7663Kb)  |  Favorite  |  View/Download:1/1  |  Submit date:2024/07/10
antihepatoma effects  guaianolide-germacranolide heterodimers  PDGFRA  DERIVATIVES  
UPLC-Q-Orbitrap-MS/MS-Guided Isolation of Bioactive Withanolides from the Fruits of Physalis angulata 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 44, 页码: 16581-16592
Authors:  Wang,Peng;  Yang,Xiao-Meng;  Hu,Zhan-Xing;  Li,Ya-Nan;  Yang,Jue;  Hao,Xiao-Jiang;  Yuan,Chun-Mao;  Yi,Ping
View  |  Adobe PDF(3336Kb)  |  Favorite  |  View/Download:2/1  |  Submit date:2024/07/10
Physalis angulata  rare withanolidederivatives  isolation and identification  anticancer  anti-inflammatory activity  CYTOTOXIC WITHANOLIDES  CONSTITUENTS  PLANTS  L.