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Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
Authors:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
Authors:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
View  |  Adobe PDF(3047Kb)  |  Favorite  |  View/Download：145/2  |  Submit date：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
一种HCV抑制剂中间体9-羟基-6-氧-4-甲基菲啶的全合成 期刊论文
云南民族大学学报(自然科学版), 2016, 期号: 6, 页码: 499-502
Authors:  杨碧娟;  刘广锦;  郭晶晶;  景晨旭;  陈铎之;  郝小江
View  |  Adobe PDF(223Kb)  |  Favorite  |  View/Download：259/30  |  Submit date：2016/12/19
全合成  9-羟基-6-氧-4-甲基菲啶  钯催化烷基-烷基  N-芳基一步偶联  
Physiological and Proteomic Adaptation of the Alpine Grass Stipa purpurea to a Drought Gradient 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 2, 页码: e0117475
Authors:  Yang, Yunqiang;  Dong, Chao;  Yang, Shihai;  Li, Xiong;  Sun, Xudong;  Yang, Yongping;  Sun,XD (reprint author),Chinese Acad Sci,Kunming Inst Bot,Key Lab Plant Div & Biogeog East Asia,Kunming,Peoples R China.;  sunxudong@mail.kib.ac.cn;  yangyp@mail.kib.ac.cn
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Design, Synthesis and Biological Evaluation of Caudatin Analogs as Potent Hepatitis B Virus Inhibitors 期刊论文
MEDICINAL CHEMISTRY, 2015, 卷号: 11, 期号: 2, 页码: 165-179
Authors:  Wang, Li-Jun;  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.
View  |  Adobe PDF(375Kb)  |  Favorite  |  View/Download：127/37  |  Submit date：2015/06/29
Anti-hbv Activity  Caudatin Analogs  Hepatitis b e Antigen (Hbeag)  Hepatitis b Surface Antigen (Hbsag)  Hbv Dna Replication  Structure-activity Relationships(Sars)  Synthesis  
山楝中化学成分及其生物活性研究 学位论文
, 北京: 中国科学院大学, 2013
Authors:  蔡洁云
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一类新型药物先导化合物的发现及其构效关系研究 学位论文
, 北京: 中国科学院大学, 2013
Authors:  陈铎之
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石蒜生物碱  抗hcv  Wnt 信号通路激动剂  构效关系研究  全合成  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
Authors:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
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(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity  
Therapeutic Targeting of Autophagy in Disease:Biology and Pharmacology 期刊论文
Pharmacol Rev, 2013, 卷号: 65, 期号: 0, 页码: 1162–1197
Authors:  Yan Cheng;  Xingcong Ren;  William N. Hait;  Jin-Ming Yang
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Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
Authors:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms