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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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植物化学与西部植物... [12]
昆明植物所硕博研究生... [1]
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郝小江 [12]
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Discovery of novel phenanthridone derivatives with anti-streptococcal activity
期刊论文
ARCHIVES OF MICROBIOLOGY, 2023, 卷号: 205, 期号: 12, 页码: 371
Authors:
Zhang,Shidan
;
Zhang,Shiyu
;
Wang,Yiting
;
Zhang,Yumin
;
Liang,Song
;
Fan,Shirui
;
Chen,Duozhi
;
Liu,Guangjin
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Submit date:2024/05/09
Phenanthridine derivatives
Cytotoxicity
Antibacterial activity
Streptococci
Molecular docking
RESISTANCE
CYTOTOXICITY
OPTIMIZATION
DOCKING
TRENDS
Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 3, 页码: 427-430
Authors:
Zhang, Jiahui
;
Cao, Pei
;
Ma, Yuanliang
;
Fang, Xin
;
Yang, Jing
;
Zhang, Yu
;
Chen, Duozhi
;
Gu, Yucheng
;
Di, Yingtong
;
Hao, Xiaojiang
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Submit date:2019/07/29
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
Authors:
Chen, Duozhi
;
Zhang, Heng
;
Jing, Chenxu
;
He, Xiaoli
;
Yang, Bijuan
;
Cai, Jieyun
;
Zhou, Yunfu
;
Song, Xiaoming
;
Li, Lin
;
Hao, Xiaojiang
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Submit date:2018/11/12
Wnt/beta-catenin signaling agonist
Phenanthridine derivatives
Structural optimization
一种HCV抑制剂中间体9-羟基-6-氧-4-甲基菲啶的全合成
期刊论文
云南民族大学学报(自然科学版), 2016, 期号: 6, 页码: 499-502
Authors:
杨碧娟
;
刘广锦
;
郭晶晶
;
景晨旭
;
陈铎之
;
郝小江
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Submit date:2016/12/19
全合成
9-羟基-6-氧-4-甲基菲啶
钯催化烷基-烷基
N-芳基一步偶联
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition
期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
Authors:
Chen,Duozhi
;
Cai,Jieyun
;
Cheng,Junjun
;
Jing,Chenxu
;
Yin,Junlin
;
Jiang,Jiandong
;
Peng,Zonggen
;
Hao,Xiaojiang
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Submit date:2016/01/19
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors
期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
Authors:
Chen, Duozhi
;
Cai, Jieyun
;
Yin, Junlin
;
Jiang, Jiandong
;
Jing, Chenxu
;
Zhu, Yanping
;
Cheng, Junjun
;
Di, Yingtong
;
Zhang, Yu
;
Cao, Mingming
;
Li, Shunlin
;
Peng, Zonggen
;
Hao, Xiaojiang
;
Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.
;
haoxj@mail.kib.ac.cn
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Submit date:2015/07/20
New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa
期刊论文
FITOTERAPIA, 2015, 卷号: 100, 页码: 150-155
Authors:
Zhang, Yu
;
Guo, Lingli
;
Yang, Guangmei
;
Guo, Feng
;
Di, Yingtong
;
Li, Shunlin
;
Chen, Duozhi
;
Hao, Xiaojiang
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Adobe PDF(553Kb)
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View/Download:376/113
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Submit date:2015/06/17
Tabernaemontana Corymbosa
Bisindole Alkaloids
Tabercorines A-c
Cytotoxicity
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction
期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
Authors:
Wang, Sheng
;
Yin, Junlin
;
Chen, Duozhi
;
Nie, Fen
;
Song, Xiaomin
;
Fei, Cong
;
Miao, Haofei
;
Jing, Changbin
;
Ma, Wenjing
;
Wang, Lei
;
Xie, Sichun
;
Li, Chen
;
Zeng, Rong
;
Pan, Weijun
;
Hao, Xiaojiang
;
Li, Lin
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Adobe PDF(1157Kb)
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View/Download:663/140
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Submit date:2013/10/16
Glycogen-synthase Kinase-3
Beta-catenin
Negative Regulator
Dix Domain
Stem-cells
In-vivo
Axin
Activation
Pathway
Phosphorylation
一类新型药物先导化合物的发现及其构效关系研究
学位论文
, 北京: 中国科学院大学, 2013
Authors:
陈铎之
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Submit date:2016/05/31
石蒜生物碱
抗hcv
Wnt 信号通路激动剂
构效关系研究
全合成
三氮唑类化合物,其药物组合物和其制备方法与应用
专利
申请日期: 2013-03-13, 公开日期: 2014-09-10
Inventors:
郝小江
;
陈铎之
;
尹俊林
;
李林
;
汪胜
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Submit date:2018/05/10