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Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 3, 页码: 427-430
Authors:  Zhang, Jiahui;  Cao, Pei;  Ma, Yuanliang;  Fang, Xin;  Yang, Jing;  Zhang, Yu;  Chen, Duozhi;  Gu, Yucheng;  Di, Yingtong;  Hao, Xiaojiang
Favorite  |  View/Download:22/0  |  Submit date:2019/07/29
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
Favorite  |  View/Download:294/0  |  Submit date:2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
Efficient synthesis of new phenanthridine Wnt/b-catenin signaling pathway agonists 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Duozhi Chen;  Heng Zhang;  Chenxu Jing;  Xiaoli He;  Bijuan Yang;  Jieyun Cai;  Yunfu Zhou;  Xiaoming Song;  Lin Li;  Xiaojiang Hao
View  |  Adobe PDF(1966Kb)  |  Favorite  |  View/Download:68/30  |  Submit date:2019/03/27
一种HCV抑制剂中间体9-羟基-6-氧-4-甲基菲啶的全合成 期刊论文
云南民族大学学报(自然科学版), 2016, 期号: 6, 页码: 499-502
Authors:  杨碧娟;  刘广锦;  郭晶晶;  景晨旭;  陈铎之;  郝小江
View  |  Adobe PDF(223Kb)  |  Favorite  |  View/Download:222/25  |  Submit date:2016/12/19
全合成  9-羟基-6-氧-4-甲基菲啶  钯催化烷基-烷基  N-芳基一步偶联  
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
Authors:  Chen,Duozhi;  Cai,Jieyun;  Cheng,Junjun;  Jing,Chenxu;  Yin,Junlin;  Jiang,Jiandong;  Peng,Zonggen;  Hao,Xiaojiang
View  |  Adobe PDF(833Kb)  |  Favorite  |  View/Download:55/20  |  Submit date:2016/01/19
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
Authors:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
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New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa 期刊论文
FITOTERAPIA, 2015, 卷号: 100, 页码: 150-155
Authors:  Zhang, Yu;  Guo, Lingli;  Yang, Guangmei;  Guo, Feng;  Di, Yingtong;  Li, Shunlin;  Chen, Duozhi;  Hao, Xiaojiang
View  |  Adobe PDF(553Kb)  |  Favorite  |  View/Download:191/37  |  Submit date:2015/06/17
Tabernaemontana Corymbosa  Bisindole Alkaloids  Tabercorines A-c  Cytotoxicity  
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
Authors:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
View  |  Adobe PDF(1157Kb)  |  Favorite  |  View/Download:488/82  |  Submit date:2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
一类新型药物先导化合物的发现及其构效关系研究 学位论文
, 北京: 中国科学院大学, 2013
Authors:  陈铎之
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石蒜生物碱  抗hcv  Wnt 信号通路激动剂  构效关系研究  全合成  
三氮唑类化合物,其药物组合物和其制备方法与应用 专利
申请日期: 2013-03-13, 公开日期: 2014-09-10
Inventors:  郝小江;  陈铎之;  尹俊林;  李林;  汪胜
Favorite  |  View/Download:16/0  |  Submit date:2018/05/10