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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
Authors:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
View  |  Adobe PDF(3047Kb)  |  Favorite  |  View/Download:112/0  |  Submit date:2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
Favorite  |  View/Download:298/0  |  Submit date:2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
Authors:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
Favorite  |  View/Download:344/0  |  Submit date:2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Plants traditionally used to make Cantonese slow-cooked soup in China 期刊论文
Journal of Ethnobiology and Ethnomedicine, 2018, 卷号: 14, 期号: 1
Authors:  Liu,Yujing;  Liu,Qi;  Li,Ping;  Xing,Deke;  Hu,Huagang;  Li,Lin;  Hu,Xuechen;  Long,Chunlin
Favorite  |  View/Download:18/0  |  Submit date:2018/09/27
Cantonese slow-cooked soup  Ethnomedicine  Botanical industry  Food therapy  Cultural significance indices  
A Plants traditionally used to make Cantonese slow-cooked soup in China 期刊论文
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE, 2018, 卷号: 14, 页码: 4
Authors:  Liu, Yujing;  Liu, Qi;  Li, Ping;  Xing, Deke;  Hu, Huagang;  Li, Lin;  Hu, Xuechen;  Long, Chunlin
Favorite  |  View/Download:30/0  |  Submit date:2018/05/08
Cantonese Slow-cooked Soup  Ethnomedicine  Botanical Industry  Food Therapy  Cultural Significance Indices  
PEROXIREDOXIN1 IS A THERAPEUTIC TARGET IN GROUP-3 MEDULLOBLASTOMA 期刊论文
NEURO-ONCOLOGY, 2017, 卷号: 19, 页码: 200-200
Authors:  Babu, Sajesh;  Omar, Refaat;  Fediuk, Holly;  Li, Lin;  Coudiere-Morrision, Ludivine;  Wang, W.;  Pu, J.;  Sun, H. D.;  Werbowetski-Ogilvie, Tamra;  Woelfl, Matthias;  Remke, Marc;  Taylor, Michael;  Eberhart, Charles;  Symons, Marc;  Ruggieri, Rosamaria;  Vanan, Magimairajan Issai
Favorite  |  View/Download:42/0  |  Submit date:2018/05/08
无权访问的条目 演示报告
Authors:  林伟立;  张晓春
Microsoft Powerpoint(19649Kb)  |  Favorite  |  View/Download:0/0  |  Submit date:2019/05/24
无权访问的条目 演示报告
Authors:  李林辉
Microsoft Powerpoint(1725Kb)  |  Favorite  |  View/Download:0/0  |  Submit date:2019/05/24
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 0, 页码: 42176
Authors:  Li, Mingyue;  Song, Li-Hua;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Zhao, Li-Mei;  Li, Lin;  Zhou, Xunian;  Tsui, Stephen Kwok-Wing;  Ng, Simon Siu-Man;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
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Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
Authors:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
View  |  Adobe PDF(3775Kb)  |  Favorite  |  View/Download:52/3  |  Submit date:2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling