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The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
Authors:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
Favorite  |  View/Download:320/0  |  Submit date:2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
Authors:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
View  |  Adobe PDF(3138Kb)  |  Favorite  |  View/Download:601/85  |  Submit date:2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
一种降齐墩果酸化合物抑制脂肪细胞分化和调节脂代谢的机理初探 学位论文
: 中国科学院大学, 2017
Authors:  彭莉
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USP7 作为结直肠肿瘤治疗靶点的研究 学位论文
: 中国科学院大学, 2017
Authors:  安涛
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GLA 靶向Wnt 信号通路抑制结直肠肿瘤的研究 学位论文
: 中国科学院大学, 2017
Authors:  龚雅潇
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Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
Authors:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
View  |  Adobe PDF(3775Kb)  |  Favorite  |  View/Download:38/1  |  Submit date:2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
Authors:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
View  |  Adobe PDF(1017Kb)  |  Favorite  |  View/Download:140/7  |  Submit date:2017/02/14
Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
Authors:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
View  |  Adobe PDF(7290Kb)  |  Favorite  |  View/Download:73/12  |  Submit date:2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
Bisleuconothine A和Eriocalyxin B抗肿瘤作用机制研究 学位论文
, 昆明: 中国科学院大学, 2015
Authors:  孔令梅
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Wnt信号通路  Bisleuconothine a  抗肿瘤活性  Eriocalyxin b  Nf-κb信号通路  P50  
Ginkgetin和4βHWE的抗肿瘤活性及机制研究 学位论文
, 昆明: 中国科学院大学, 2015
Authors:  叶蓁楠
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Wnt/β-catenin  小分子抑制剂  Ginkgetin  醉茄内酯  髓母细胞瘤  结肠癌