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Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 33-34
作者:  Wu, Ya;  Li, Hao;  Yan, Jiao;  Cai, Qing;  Huang, Shengxiong;  Tang, Ying;  Ji, Yue;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：201/0  |  提交时间：2020/03/24
Aromatization of natural products by a specialized detoxification enzyme 期刊论文
NATURE CHEMICAL BIOLOGY, 2020, 卷号: 16, 期号: 3, 页码: 11
作者:  Huang, Jin-Quan;  Fang, Xin;  Tian, Xiu;  Chen, Ping;  Lin, Jia-Ling;  Guo, Xiao-Xiang;  Li, Jian-Xu;  Fan, Zhen;  Song, Wei-Meng;  Chen, Fang-Yan;  Ahati, Ruzha;  Wang, Ling-Jian;  Zhao, Qing;  Martin, Cathie;  Chen, Xiao-Ya
收藏  |  浏览/下载：137/0  |  提交时间：2020/03/18
Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 22, 页码: 9272-9275
作者:  Zhang, Yu;  Ding, Xiao;  Shao, Shun;  Guo, Ling-Li;  Zhao, Qing;  Hao, Xiao-Jiang;  He, Hong-Ping
Adobe PDF(982Kb)  |  收藏  |  浏览/下载：291/158  |  提交时间：2020/03/02
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：228/69  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：252/59  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：235/104  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities 期刊论文
FITOTERAPIA, 2019, 卷号: 134, 页码: 58-64
作者:  Lu, Shuang-Yang;  Peng, Xing-Rong;  Dong, Jin-Run;  Yan, Hui;  Kong, Qing-Hua;  Shi, Qiang-Qiang;  Li, Da-Shan;  Zhou, Lin;  Li, Zhong-Rong;  Qiu, Ming-Hua
Adobe PDF(556Kb)  |  收藏  |  浏览/下载：214/65  |  提交时间：2019/07/29
Ganoderma lucidum  Aromatic constituents  Neuroprotective activity  Anti-inflammatory activity  Depression  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：159/34  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
Adobe PDF(500Kb)  |  收藏  |  浏览/下载：423/188  |  提交时间：2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 3683-3692
作者:  Zi, Cheng-Ting;  Yang, Liu;  Kong, Qing-Hua;  Li, Hong-Mei;  Yang, Xing-Zhi;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Zhou, Jun
Adobe PDF(3776Kb)  |  收藏  |  浏览/下载：151/19  |  提交时间：2020/03/26
podophyllotoxin  glucoside  synthesis  cytotoxicity  physicochemical properties