Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis

doi:10.1021/acs.orglett.9b03785

	Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis
	Zhang, Yu1 ; Ding, Xiao 1; Shao, Shun 2; Guo, Ling-Li1 ; Zhao, Qing 2; Hao, Xiao-Jiang1 ; He, Hong-Ping 2
通讯作者	Hao, Xiao-Jiang(hehongping@yahoo.com) ; He, Hong-Ping(haoxj@mail.kib.ac.cn)
	2019-11-15
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	21 期号:22 页码:9272-9275
摘要	Melocochines A (1) and B (2), one pair of epimers with an unprecedented skeleton, were isolated from Melodinus cochinchinensis. Their structures and absolute configurations were established by a combination of MS, NMR, and single-crystal X-ray diffraction analyses. Compounds 1 and 2 represent a class of novel alkaloids, characterized by a rare 1H-benzo[b]azepane ring system within monoterpenoid indole alkaloid categories. Compounds 1 and 2 enhanced lysosomal biogenesis with LysoTracker staining intensities of 139.7% and 119.0%, respectively.
DOI	10.1021/acs.orglett.9b03785
收录类别	SCI ; SCI
语种	英语
WOS记录号	WOS:000497259500086
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/70115
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Hao, Xiao-Jiang; He, Hong-Ping
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yu,Ding, Xiao,Shao, Shun,et al. Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis[J]. ORGANIC LETTERS,2019,21(22):9272-9275.
APA	Zhang, Yu.,Ding, Xiao.,Shao, Shun.,Guo, Ling-Li.,Zhao, Qing.,...&He, Hong-Ping.(2019).Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis.ORGANIC LETTERS,21(22),9272-9275.
MLA	Zhang, Yu,et al."Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis".ORGANIC LETTERS 21.22(2019):9272-9275.

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Zhang-2019-Melocochi（982KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览下载