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Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
Authors:  Guo,Xiuping;  Li,Rui;  Cui,Jinjin;  Hu,Chujuan;  Yu,Haoyang;  Ren,Ling;  Cheng,Yangyang;  Jiang,Jiandong;  Ding,Xiao;  Wang,Lulu
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Erigeron breviscapus injection  Dengzhanxixin  Erigeron breviscapus (Vant  ) Hand  -Mazz  colorectal cancer  necroptosis  drug resistance  TUMOR-NECROSIS-FACTOR  COLORECTAL-CANCER  NATURAL COMPOUNDS  SCUTELLARIN  APOPTOSIS  PROLIFERATION  MACROPHAGES  MIGRATION  INVASION  THERAPY  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
Authors:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
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Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Honoring a legend: Celebrating the life and legacy of Professor Heng Li 期刊论文
PLANT DIVERSITY, 2023, 卷号: 45, 期号: 3, 页码: 239-240
Authors:  Guo,Hui-Jun;  Huang,Jin-Ling;  Ji,Yun-Heng;  Li,Rong;  Long,Chun-Lin;  Yang,Qin-Er;  Yang,Yong-Ping;  Yi,Ting-Shuang
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A nonS-locus F-box gene breaks self-incompatibility in diploid potatoes 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 4142
Authors:  Ma,Ling;  Zhang,Chunzhi;  Zhang,Bo;  Tang,Fei;  Li,Futing;  Liao,Qinggang;  Tang,Die;  Peng,Zhen;  Jia,Yuxin;  Gao,Meng;  Guo,Han;  Zhang,Jinzhe;  Luo,Xuming;  Yang,Huiqin;  Gao,Dongli;  Lucas,William J.;  Li,Canhui;  Huang,Sanwen;  Shang,Yi
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SPECIES SOLANUM-CHACOENSE  INHIBITOR SLI GENE  NICOTIANA-ALATA  INBRED LINE  COMPATIBILITY  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
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enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
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terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Alkaloids from Tabernaemontana divaricata combined with fluconazole to overcome fluconazole resistance in Candida albicans 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104515
Authors:  Zhang,Yu;  Bai,Xue;  Yuwen,Huan-Sha;  Guo,Ling-Li;  Liu,Jian-Wen;  Hao,Xiao-Jiang
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Tabernaemontana divaricate  Taberdines A-K  Reversal of fluconazole resistance  Candida albicans  
Morphological distinctiveness of Ligularia tongolensis and L. cymbulifera is maintained between habitats despite bidirectional and asymmetrical introgression in multiple hybrid zones 期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2021
Authors:  Hu,Li;  Yang,Rui;  Yang,Guo-Qian;  Sun,Gui-Ling;  Gong,Xun
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ddRAD  hybrid zones  Ligularia  natural hybridization  reproductive isolation  REPRODUCTIVE ISOLATION  NATURAL HYBRIDIZATION  HENGDUAN MOUNTAINS  POPULATION-STRUCTURE  ASTERACEAE  YUNNAN  DIVERSIFICATION  PHYLOGEOGRAPHY  SPECIATION  VELLEREA  
Aromatization of natural products by a specialized detoxification enzyme 期刊论文
NATURE CHEMICAL BIOLOGY, 2020, 卷号: 16, 期号: 3, 页码: 11
Authors:  Huang, Jin-Quan;  Fang, Xin;  Tian, Xiu;  Chen, Ping;  Lin, Jia-Ling;  Guo, Xiao-Xiang;  Li, Jian-Xu;  Fan, Zhen;  Song, Wei-Meng;  Chen, Fang-Yan;  Ahati, Ruzha;  Wang, Ling-Jian;  Zhao, Qing;  Martin, Cathie;  Chen, Xiao-Ya
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Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020
Authors:  Zhang, Yu;  Ding, Xiao;  Yuan, Yu-Xi;  Guo, Ling-Li;  Hao, Xiao-Jiang
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