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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
浏览  |  Adobe PDF(11543Kb)  |  收藏  |  浏览/下载：22/5  |  提交时间：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep. 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 10, 页码: 4394-4407
作者:  Zhao,Li-Hua;  Hu,Zhan-Xing;  Hao,Xiao-Jiang;  Zhang,Peng;  Zhang,Ji;  An,Qiao;  Wang,Juan;  Yi,Ping;  Yuan,Chun-Mao;  Zhang,Zhong-Kai
浏览  |  Adobe PDF(4497Kb)  |  收藏  |  浏览/下载：30/14  |  提交时间：2024/07/10
Sophora tonkinensis Gagnep  matrine-type alkaloids  anti-TSWV  LUPIN ALKALOIDS  QUINOLIZIDINE ALKALOIDS  SEEDS  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
浏览  |  Adobe PDF(10283Kb)  |  收藏  |  浏览/下载：19/9  |  提交时间：2024/07/30
Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：148/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Three new diterpenoids fromEuphorbia peplus 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 21, 页码: 3901-3907
作者:  Chen,Yan-Ni;  Lu,Qing-Yun;  Li,Dong-Mei;  Li,Ying-Yao;  Pu,Xue-Xue;  Li,Bo-Ting;  Tang,Xiao-Han;  Tang,Hong-Yu;  Liu,Shuai;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(374Kb)  |  收藏  |  浏览/下载：143/40  |  提交时间：2022/04/02
Euphorbiaceae  Euphorbia peplus  ent-abietane diterpenoids  paralianone diterpenoids  EUPHORBIA-PEPLUS  STEMS  
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu,Shuai;  Zhang,Cui-Shan;  Ran,Xiao-Qian;  Tang,Xiao-Han;  Guo,Ya-Rong;  Yan,Ying;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rong-Can;  Di,Ying-Tong
浏览  |  Adobe PDF(997Kb)  |  收藏  |  浏览/下载：143/46  |  提交时间：2022/04/02
PROMISING BIOLOGICAL-ACTIVITY  LIMONOIDS  CHROMONES  FRUITS  DRUG  
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
作者:  Zeng,Yan-Rong;  Li,Ya-Nan;  Yang,Jue;  Yi,Ping;  Huang,Lei;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Li,Yan-Mei;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2840Kb)  |  收藏  |  浏览/下载：114/31  |  提交时间：2022/04/02
Hypericum monogynum  Phytochemistry  Structure elucidation  Biological activity  Multidrug resistance reversal activity  P-GLYCOPROTEIN  MODULATORS  CANCER  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：191/62  |  提交时间：2023/09/08
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 3, 页码: 357-364
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Lu,Qing-Yun;  Liu,Shuai;  Li,Ying-Yao;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1584Kb)  |  收藏  |  浏览/下载：149/33  |  提交时间：2022/04/02
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：143/45  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70