Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway.

doi:10.1007/s13659-021-00301-4

KIB OpenIR

	Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway.
	Chen,Yan-Ni; Ding,Xiao; Li,Dong-Mei; Lu,Qing-Yun; Liu,Shuai; Li,Ying-Yao; Di,Ying-Tong; Fang,Xin; Hao,Xiao-Jiang
	2021
Source Publication	Natural products and bioprospecting
ISSN	2192-2195
Volume	11 Issue:3 Pages:357-364
Abstract	Euphopepluanones F-K (1-4), four new jatrophane type diterpenoids were isolated from the seeds of Euphorbia peplus, along with eight known diterpenoids (5-12). Their structures were established on the basis of extensive spectroscopic analysis and X-ray crystallographic experiments. The new compounds 1-4 were assessed for their activities to induce lysosomal biogenesis through LysoTracker Red staining. Compound 2 significantly induced lysosomal biogenesis. In addition, compound 2 could increase the number of LC3 dots, indicating that it could activate the lysosomal-autophagy pathway.
DOI	10.1007/s13659-021-00301-4
Citation statistics
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/73805
Collection	中国科学院昆明植物研究所
Recommended Citation GB/T 7714	Chen,Yan-Ni,Ding,Xiao,Li,Dong-Mei,et al. Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway.[J]. Natural products and bioprospecting,2021,11(3):357-364.
APA	Chen,Yan-Ni.,Ding,Xiao.,Li,Dong-Mei.,Lu,Qing-Yun.,Liu,Shuai.,...&Hao,Xiao-Jiang.(2021).Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway..Natural products and bioprospecting,11(3),357-364.
MLA	Chen,Yan-Ni,et al."Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway.".Natural products and bioprospecting 11.3(2021):357-364.

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