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Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
Authors:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
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ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
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Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Leucoabietenes A and B, rearranged abietane and ent-abietane diterpene hydrocarbons against resistant infectious fungus and bacterium from the leaves of Leucosceptrum canum 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 81, 页码: 153356
Authors:  Zhang,Man-Wen;  Guo,Kai;  Zhang,Yu;  Teng,Lin-Lin;  Huang,Qing-Pu;  Liu,Yan;  Li,Sheng-Hong
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Leucosceptrum canum  Ent-abietane diterpene  Abietane diterpene  Antimicrobial activity  TERPENOIDS  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
Authors:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
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Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
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Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
Authors:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
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Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Hydroxynitrile Glucosides: Bioactive Constituent Recovery from the Oil Residue of Prinsepia utilis 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 8, 页码: 2438-2443
Authors:  Shi,Qiang-Qiang;  Lu,Shuang-Yang;  Peng,Xing-Rong;  Zhou,Lin;  Qiu,Ming-Hua
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Prinsepia utilis oil residue  gamma-hydroxynitrile glucosides  alpha-glucosidase inhibitor  CHEMICAL-CONSTITUENTS  LEAVES  BIOSYNTHESIS  FLAVONOIDS  SEEDS  
Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 73, 页码: 153133
Authors:  Chen,Su-Ping;  Hu,Kun;  Li,Xing-Ren;  Zhang,Liang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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Isodon scoparius  Meroditerpenoid  Residual dipolar coupling  Immunosuppressive activity  Antimicrobial activity  ENT-KAURANE DITERPENOIDS  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT  
High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activities 期刊论文
CELL BIOLOGY AND TOXICOLOGY, 2021, 卷号: 37, 期号: 5, 页码: 695-713
Authors:  Huang,Lihong;  Fu,Qiang;  Dai,Jia-Meng;  Yan,Bing-Chao;  Wang,Dawei;  Puno,Pema-Tenzin;  Yue,Jianbo
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Diterpenoids  Autophagy  Lysosome  Autophagosome  Enanderinanin J  Dengue virus (DENV)  Zika virus (ZIKV)  Japanese encephalitis virus (JEV)  Enterovirus-A71 (EV-A71)