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Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius
Chen,Su-Ping; Hu,Kun; Li,Xing-Ren; Zhang,Liang; Sun,Han-Dong; Puno,Pema-Tenzin
2021
Source PublicationTETRAHEDRON LETTERS
ISSN0040-4039
Volume73Pages:153133
AbstractScopariusicide C (1), a novel ent-clerodane-based meroditerpenoid was isolated from artificially cultivated Isodon scoparius. An oxygen insertion reaction proposed to occur in its biosynthesis makes its scaffold different from those meroterpenoids previously isolated from the same species. The structure of 1 was determined by analysis of spectroscopic data, quantum chemical calculations and use of residual dipolar coupling (RDC). 1 showed moderate inhibitory effects against T and B lymphocyte proliferation and good anti-MRSA activity. (C) 2021 Elsevier Ltd. All rights reserved.
KeywordIsodon scoparius Meroditerpenoid Residual dipolar coupling Immunosuppressive activity Antimicrobial activity ENT-KAURANE DITERPENOIDS
DOI10.1016/j.tetlet.2021.153133
WOS IDWOS:000656983400030
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/73361
Collection中国科学院昆明植物研究所
Affiliation1.[Chen, Su-Ping
2.Hu, Kun
3.Li, Xing-Ren
4.Zhang, Liang
5.Sun, Han-Dong
6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
7.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Chen,Su-Ping,Hu,Kun,Li,Xing-Ren,et al. Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius[J]. TETRAHEDRON LETTERS,2021,73:153133.
APA Chen,Su-Ping,Hu,Kun,Li,Xing-Ren,Zhang,Liang,Sun,Han-Dong,&Puno,Pema-Tenzin.(2021).Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius.TETRAHEDRON LETTERS,73,153133.
MLA Chen,Su-Ping,et al."Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius".TETRAHEDRON LETTERS 73(2021):153133.
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