Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius

doi:10.1016/j.tetlet.2021.153133

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	Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius
	Chen,Su-Ping ; Hu,Kun; Li,Xing-Ren ; Zhang,Liang ; Sun,Han-Dong; Puno,Pema-Tenzin
	2021
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	73 页码:153133
摘要	Scopariusicide C (1), a novel ent-clerodane-based meroditerpenoid was isolated from artificially cultivated Isodon scoparius. An oxygen insertion reaction proposed to occur in its biosynthesis makes its scaffold different from those meroterpenoids previously isolated from the same species. The structure of 1 was determined by analysis of spectroscopic data, quantum chemical calculations and use of residual dipolar coupling (RDC). 1 showed moderate inhibitory effects against T and B lymphocyte proliferation and good anti-MRSA activity. (C) 2021 Elsevier Ltd. All rights reserved.
关键词	Isodon scoparius Meroditerpenoid Residual dipolar coupling Immunosuppressive activity Antimicrobial activity ENT-KAURANE DITERPENOIDS
DOI	10.1016/j.tetlet.2021.153133
WOS记录号	WOS:000656983400030
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73361
专题	中国科学院昆明植物研究所
作者单位	1.[Chen, Su-Ping 2.Hu, Kun 3.Li, Xing-Ren 4.Zhang, Liang 5.Sun, Han-Dong 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 7.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen,Su-Ping,Hu,Kun,Li,Xing-Ren,et al. Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius[J]. TETRAHEDRON LETTERS,2021,73:153133.
APA	Chen,Su-Ping,Hu,Kun,Li,Xing-Ren,Zhang,Liang,Sun,Han-Dong,&Puno,Pema-Tenzin.(2021).Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius.TETRAHEDRON LETTERS,73,153133.
MLA	Chen,Su-Ping,et al."Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius".TETRAHEDRON LETTERS 73(2021):153133.

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