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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines
期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:
Ming-Ju Hsieh
;
Chiao-Wen Lin
;
Shun-Fa Yang
;
Mu-Kuan Chen
;
Hui-Ling Chiou
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Submit date:2017/07/24
Glabridin
Migration
Invasion
Matrix Metalloproteinase-9
Hepatoma
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
;
Che-Ming Teng
;
Min-Tsang Hsieh
;
Hsin-Yi Hung
;
Li-Jiau Huang
;
Yung-Luen Yu
;
Sheng-Chu Kuo
Adobe PDF(1357Kb)
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Submit date:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
Design and synthesis of guaianolide-germacranolide heterodimers as novel anticancer agents against hepatocellular carcinoma
期刊论文
DRUG DEVELOPMENT RESEARCH, 2023
Authors:
Yan,Jia-Xin
;
Li,Qi-Hao
;
Li,Tian-Ze
;
Huang,Zhi-Yan
;
Ma,Yun-Bao
;
Chen,Ji-Jun
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Submit date:2024/07/10
antihepatoma effects
guaianolide-germacranolide heterodimers
PDGFRA
DERIVATIVES
Phytochemical Analysis of Nothapodytes tomentosa and Distribution and Content of Camptothecin and its Analogues in Four Plants
期刊论文
PLANTA MEDICA, 2023, 卷号: 89, 期号: 13, 页码: 1250-1258
Authors:
Li,Junheng
;
Chen,Yin
;
Wu,Lei
;
Tuo,Xiaotao
;
Wang,Li
;
Zhou,Guanglian
;
Huang,Sheng-Xiong
;
Xiong,Wei
;
Huang,Jian-Ping
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Submit date:2024/07/30
Nothapodytes tomentosa
Nothapodytes nimmoniana
Camptotheca acuminata
Ophiorrhiza japonica
Icacinaceae
camptothecin derivatives
ANTITUMOR AGENTS
ACID-ESTER
9-METHOXYCAMPTOTHECIN
IDENTIFICATION
CONSTITUENTS
ALKALOIDS
MEDICINE
FRUITS
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel
期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:
Hu,Guilin
;
Dong,Ding
;
Du,Shuzong
;
Peng,Xingrong
;
Wu,Mingkun
;
Shi,Qiangqiang
;
Hu,Kun
;
Hong,Defu
;
Wang,Xiaoyuan
;
Zhou,Lin
;
Nian,Yin
;
Qiu,Minghua
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Submit date:2022/04/02
Coffea arabica L
Roasted coffee
Coffee diterpenoid
Cafestol
Kahweol
T-type Ca2+ channels
Ca(v)3.1 low voltage-gated Ca2+ channel
Ca(v)3.1 inhibitors
CALCIUM-CHANNELS
CAFESTOL
KAHWEOL
PHYSIOLOGY
ESTERS
NOMENCLATURE
PHARMACOLOGY
APOPTOSIS
FURANS
Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 7, 页码: 1224-1239
Authors:
Sun, Jin-Jin
;
Wang, Jin-Ping
;
Li, Tian-Ze
;
Ma, Yun-Bao
;
Xue, Dong
;
Chen, Ji-Jun
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Submit date:2024/04/30
Ludartin derivatives
Antihepatoma activity
HepG2 cells
Huh7 cells
SESQUITERPENE LACTONES
CHEMICAL-CONSTITUENTS
GUAIANOLIDES
ANTITUMOR
ANALOGS
Reviewing the world's edible mushroom species: A new evidence-based classification system
期刊论文
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2021
Authors:
Li,Huili
;
Tian,Yang
;
Menolli Jr,Nelson
;
Ye,Lei
;
Karunarathna,Samantha C.
;
Perez-Moreno,Jesus
;
Rahman,Mohammad Mahmudur
;
Rashid,Md Harunur
;
Phengsintham,Pheng
;
Rizal,Leela
;
Kasuya,Taiga
;
Lim,Young Woon
;
Dutta,Arun Kumar
;
Khalid,Abdul Nasir
;
Le Thanh Huyen
;
Balolong,Marilen Parungao
;
Baruah,Gautam
;
Madawala,Sumedha
;
Thongklang,Naritsada
;
Hyde,Kevin D.
;
Kirk,Paul M.
;
Xu,Jianchu
;
Sheng,Jun
;
Boa,Eric
;
Mortimer,Peter E.
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Submit date:2023/09/08
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
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Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift
期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
Authors:
Zhang,Xin-Tian
;
Hu,Jing
;
Su,Li-Hua
;
Geng,Chang-An
;
Chen,Ji-Jun
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Submit date:2022/04/02
Artemisia atrovirens
Cervical cancer
ERK pathway
Cell metabolism
ALKALINE-PHOSPHATASE
SIGNALING PATHWAY
DIFFERENTIATION
APOPTOSIS
ERK
MECHANISMS
Structure Revision of Four Classes of Prenylated Aromatic Natural Products Based on a Rule for Diagnostic C-13 NMR Chemical Shifts
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 16, 页码: 10982-10990
Authors:
Ren,Fu-Cai
;
Wang,Li-Xia
;
Lv,Yong-Feng
;
Hu,Jiang-Miao
;
Zhou,Jun
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Submit date:2022/04/02
ISOPRENYLATED FLAVONOIDS
CONSTITUENTS
DERIVATIVES
ANALOGS