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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载：20/10  |  提交时间：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
作者:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
浏览  |  Adobe PDF(13950Kb)  |  收藏  |  浏览/下载：15/4  |  提交时间：2024/07/25
Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：48/12  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载：353/0  |  提交时间：2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
Effect of CYP3A4 on liver injury induced by triptolide 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020
作者:  Xiao, Xuerong;  Zhang, Ting;  Huang, Jianfeng;  Zhao, Qi;  Li, Fei
Adobe PDF(4498Kb)  |  收藏  |  浏览/下载：154/46  |  提交时间：2021/01/05
Celastrol ameliorates acute liver injury through modulation of PPAR alpha 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020
作者:  Zhao, Qi;  Tang, Ping;  Zhang, Ting;  Huang, Jian-Feng;  Xiao, Xue-Rong;  Zhu, Wei-Feng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(6195Kb)  |  收藏  |  浏览/下载：136/42  |  提交时间：2021/01/05
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：276/52  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
作者:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(4782Kb)  |  收藏  |  浏览/下载：202/64  |  提交时间：2019/07/29
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
作者:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(5774Kb)  |  收藏  |  浏览/下载：342/72  |  提交时间：2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS