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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：173/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Thalicfoetine, a novel isoquinoline alkaloid with antibacterial activity from Thalictrum foetidum 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 41, 页码: 3
作者:  Ding, Cai-Feng;  Qin, Xu-Jie;  Yu, Hao-Fei;  Liu, Ya-Ping;  Wang, Xin-Hua;  Luo, Xiao-Dong
浏览  |  Adobe PDF(605Kb)  |  收藏  |  浏览/下载：186/53  |  提交时间：2019/12/20
Benzylisoquinoline alkaloid  Thalictrum foetidum  Thalicfoetine  Antimicrobial activity  
Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 19, 页码: 3428-3434
作者:  Ding, Cai-Feng;  Zhang, Rong-Ping;  Yu, Hao-Fei;  Yang, Jing;  Qin, Xu-Jie;  Dai, Zhi;  Liu, Ya-Ping;  Lu, Qiu-Min;  Lai, Ren;  Luo, Xiao-Dong
浏览  |  Adobe PDF(2565Kb)  |  收藏  |  浏览/下载：190/31  |  提交时间：2019/11/07
New aporphine alkaloids with selective cytotoxicity against glioma stem cells from Thalictrum foetidum 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 9, 页码: 698-706
作者:  Ding Cai-Feng;  Dai Zhi;  Yu Hao-Fei;  Zhao Xu-Dong;  Luo Xiao-Dong
浏览  |  Adobe PDF(3366Kb)  |  收藏  |  浏览/下载：185/77  |  提交时间：2019/10/28
Thalictrum foetidum  Aporphine alkaloids  Selective cytotoxicity  Glioma stem cells  
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载：238/40  |  提交时间：2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol  
One-Step Semisynthesis of a Segetane Diterpenoid from a Jatrophane Precursor via a Diels-Alder Reaction 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 3, 页码: 496-499
作者:  Wan, Luo-Sheng;  Shao, Li-Dong;  Fu, Liangbing;  Xu, Jun;  Zhu, Guo-Lei;  Peng, Xing-Rong;  Li, Xiao-Nian;  Li, Yan;  Qiu, Ming-Hua
浏览  |  Adobe PDF(584Kb)  |  收藏  |  浏览/下载：207/60  |  提交时间：2016/06/27
Steroidal saponins with cytotoxic activity from the rhizomes of Paris polyphylla var. yunnanensis 期刊论文
PHYTOCHEMISTRY LETTERS, 2015, 卷号: 12, 页码: 31-34
作者:  Wen, Yan-Shi;  Ni, Wei;  Qin, Xu-Jie;  Yan, Huan;  Chen, Chang-Xiang;  Hua, Yan;  Cheng, Yung-Chi;  He, Li;  Liu, Hai-Yang;  Liu,HY (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  haiyangliu@mail.kib.ac.cn
Adobe PDF(635Kb)  |  收藏  |  浏览/下载：230/81  |  提交时间：2015/07/20
Paris Polyphylla Var. Yunnanensis  Steroidal Saponins  Dianchonglouoside a  Dianchonglouoside b  Cytotoxic Activity  
Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 5, 页码: e0127092
作者:  Liu, Yanchun;  Yang, Hui;  Chen, Tianxing;  Luo, Yongbin;  Xu, Zheyuan;  Li, Ying;  Yang, Jiahui;  Yang,JH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  yangjiahui@mail.kib.ac.cn
Adobe PDF(1997Kb)  |  收藏  |  浏览/下载：256/73  |  提交时间：2015/07/20
The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats 期刊论文
HORMONES AND BEHAVIOR, 2015, 卷号: 69, 期号: 1, 页码: 106-115
作者:  Yu,Dafu;  Zhou,Heng;  Yang,Yuan;  Jiang,Yong;  Wang,Tianchao;  Lv,Liang;  Zhou,Qixin;  Yang,Yuexiong;  Dong,Xuexian;  He,Jianfeng;  Huang,Xiaoyan;  Chen,Jijun;  Wu,Kunhua;  Xu,Lin;  Mao,Rongrong;  Xu,L (reprint author),Chinese Acad Sci,Kunming Inst Zool,Lab Learning & Memory,Kunming 650223,Yunnan,Peoples R China.;  lxu@vip.163.com;  talktomaomao@163.com
Adobe PDF(867Kb)  |  收藏  |  浏览/下载：413/151  |  提交时间：2015/06/29
Hypothyroidism  Hyperthyroidism  Depression  Anxiety  Brain-derived Neurotrophic Factor  
Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 4, 页码: 2063-2084
作者:  Wu, Mingyi;  Xu, Li;  Zhao, Longyan;  Xiao, Chuang;  Gao, Na;  Luo, Lan;  Yang, Lian;  Li, Zi;  Chen, Lingyun;  Zhao, Jinhua
Adobe PDF(2239Kb)  |  收藏  |  浏览/下载：300/57  |  提交时间：2015/06/29