Thalicfoetine, a novel isoquinoline alkaloid with antibacterial activity from Thalictrum foetidum
Ding, Cai-Feng1,3,4; Qin, Xu-Jie1; Yu, Hao-Fei1,3,4; Liu, Ya-Ping1; Wang, Xin-Hua2; Luo, Xiao-Dong1,2
Corresponding AuthorWang, Xin-Hua(xinhuaw@gzhmu.edu.cn) ; Luo, Xiao-Dong(xdluo@mail.kib.ac.cn)
2019-10-10
Source PublicationTETRAHEDRON LETTERS
ISSN0040-4039
Volume60Issue:41Pages:3
AbstractThalicfoetine (1), the first O-bridged spirobenzylisoquinoline alkaloid possesses a spiro tetrahydropyridine-furanone core, was isolated from the roots of Thalictrum foetidum. Its structure was elucidated by extensive spectroscopic analyses and ECD calculation. Moreover, 1 exhibited antibacterial activity against Bacillus subtilis significantly with MIC value of 3.12 mu g/mL. (C) 2019 Elsevier Ltd. All rights reserved.
KeywordBenzylisoquinoline alkaloid Thalictrum foetidum Thalicfoetine Antimicrobial activity
DOI10.1016/j.tetlet.2019.151135
Indexed BySCI ; SCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000489357900011
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/69930
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorWang, Xin-Hua; Luo, Xiao-Dong
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Guangzhou Med Univ, State Key Lab Resp Dis, Guangzhou 510120, Guangdong, Peoples R China
3.Kunming Med Univ, Dept Zool, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China
4.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Ding, Cai-Feng,Qin, Xu-Jie,Yu, Hao-Fei,et al. Thalicfoetine, a novel isoquinoline alkaloid with antibacterial activity from Thalictrum foetidum[J]. TETRAHEDRON LETTERS,2019,60(41):3.
APA Ding, Cai-Feng,Qin, Xu-Jie,Yu, Hao-Fei,Liu, Ya-Ping,Wang, Xin-Hua,&Luo, Xiao-Dong.(2019).Thalicfoetine, a novel isoquinoline alkaloid with antibacterial activity from Thalictrum foetidum.TETRAHEDRON LETTERS,60(41),3.
MLA Ding, Cai-Feng,et al."Thalicfoetine, a novel isoquinoline alkaloid with antibacterial activity from Thalictrum foetidum".TETRAHEDRON LETTERS 60.41(2019):3.
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