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Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
作者:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
Adobe PDF(1517Kb)  |  收藏  |  浏览/下载：285/49  |  提交时间：2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：229/68  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2019, 卷号: 33, 期号: 7, 页码: 1794-1804
作者:  Li, Cong;  Xu, Huanli;  Chen, Xiaoliang;  Chen, Jijun;  Li, Xiao;  Qiao, Gan;  Tian, Ye;  Yuan, Ru;  Su, Shuonan;  Liu, Xiaohui;  Lin, Xiukun
浏览  |  Adobe PDF(1218Kb)  |  收藏  |  浏览/下载：169/44  |  提交时间：2019/09/10
AMPK  anticancer  aqueous extract of clove  autophagy  traditional Chinese medicine  
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
作者:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
浏览  |  Adobe PDF(1069Kb)  |  收藏  |  浏览/下载：168/37  |  提交时间：2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
浏览  |  Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：143/26  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
浏览  |  Adobe PDF(7335Kb)  |  收藏  |  浏览/下载：237/25  |  提交时间：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 713-717
作者:  Yan, Huan;  Qin, Xu-Jie;  Li, Xu-Hong;  Yu, Qian;  Ni, Wei;  He, Li;  Liu, Hai-Yang
浏览  |  Adobe PDF(1127Kb)  |  收藏  |  浏览/下载：247/23  |  提交时间：2019/04/15
Chloranthus japonicus  Lindenane sesquiterpenoid dimer  Japonicones A-C  ECD calculation  
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
作者:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：298/19  |  提交时间：2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
PPAR alpha Mediates the Hepatoprotective Effects of Nutmeg 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1887-1897
作者:  Yang, Xiao-Nan;  Liu, Xue-Mei;  Fang, Jian-He;  Zhu, Xu;  Yang, Xiu-Wei;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(2643Kb)  |  收藏  |  浏览/下载：259/89  |  提交时间：2018/07/02
Nutmeg  Hepatoprotective Activity  Metabolomics  Myrislignan  Ppar Alpha  
Manginoids A-G: Seven Monoterpene-Shikimate-Conjugated Meroterpenoids with a Spiro Ring System from Guignardia mangiferae 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 21, 页码: 5956-5959
作者:  Chen, Keliang;  Zhang, Xuwen;  Sun, Weiguang;  Liu, Junjun;  Yang, Jing;  Chen, Chunmei;  Liu, Xiulan;  Gao, Limin;  Wang, Jianping;  Li, Hua;  Luo, Zengwei;  Xue, Yongbo;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1771Kb)  |  收藏  |  浏览/下载：316/32  |  提交时间：2017/12/18