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Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 22, 页码: 9272-9275
作者:  Zhang, Yu;  Ding, Xiao;  Shao, Shun;  Guo, Ling-Li;  Zhao, Qing;  Hao, Xiao-Jiang;  He, Hong-Ping
浏览  |  Adobe PDF(982Kb)  |  收藏  |  浏览/下载：328/174  |  提交时间：2020/03/02
A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 9
作者:  Adelakun, Tiwalade A.;  Ding, Xiao;  Ombati, Rose M.;  Zhao, Ning-Dong;  Obodozie-Ofoegbu, Obiageri;  Di, Ying-Tong;  Zhang, Yu;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1037Kb)  |  收藏  |  浏览/下载：323/160  |  提交时间：2019/07/29
Euphorbia fischeriana Steud  highly oxygenated abietanes  phorbol esters  lysosomal biogenesis  
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3129Kb)  |  收藏  |  浏览/下载：236/26  |  提交时间：2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：328/41  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death 期刊论文
PROTEIN & CELL, 2018, 卷号: 9, 期号: 12, 页码: 1013-1026
作者:  Li, Yang;  Zhang, Yu;  Gan, Qiwen;  Xu, Meng;  Ding, Xiao;  Tang, Guihua;  Liang, Jingjing;  Liu, Kai;  Liu, Xuezhao;  Wang, Xin;  Guo, Lingli;  Gao, Zhiyang;  Hao, Xiaojiang;  Yang, Chonglin
收藏  |  浏览/下载：108/0  |  提交时间：2019/03/29
Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata 期刊论文
PHYTOCHEMISTRY LETTERS, 2016, 卷号: 18, 期号: 1, 页码: 176-179
作者:  Yuan, Wen-Juan;  Yang, Guo-Ping;  Zhang, Jia-Hui;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(558Kb)  |  收藏  |  浏览/下载：506/162  |  提交时间：2017/02/14
Euphorbiaceae  Euphorbia Ebracteolata  Diterpenes  Ebracteolatas A-c  Cytotoxic Activity  
16-nor Limonoids from Harrisonia perforata as promising selective 11 beta-HSD1 inhibitors 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 1
作者:  Xiao-HuiYan;  Yi, Ping;  Cao, Pei;  Yang, Shi-Ying;  Fang, Xin;  Zhang, Yu;  Wu, Bin;  Leng, Ying;  Di, Ying-Tong;  Lv, Yang;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1151Kb)  |  收藏  |  浏览/下载：353/57  |  提交时间：2017/01/05
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
作者:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(1560Kb)  |  收藏  |  浏览/下载：309/59  |  提交时间：2015/07/20
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：307/47  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 96, 页码: 360-369
作者:  Cheng, Yuan-Yuan;  Chen, Huan;  He, Hong-Ping;  Zhang, Yu;  Li, Shi-Fei;  Tang, Gui-Hua;  Guo, Ling-Li;  Yang, Wei;  Zhu, Feng;  Zheng, Yong-Tang;  Li, Shun-Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(973Kb)  |  收藏  |  浏览/下载：280/80  |  提交时间：2015/05/13
Trigonostemon Thyrsoideum  Euphorbiaceae  Daphnane Diterpenoids  Trigothysoids A-p  Anti-hiv-1