| Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum | |
Cheng, Yuan-Yuan1,2; Chen, Huan2,3; He, Hong-Ping1; Zhang, Yu1 ; Li, Shi-Fei1,2; Tang, Gui-Hua1,2; Guo, Ling-Li1; Yang, Wei1,2; Zhu, Feng1,2; Zheng, Yong-Tang3; Li, Shun-Lin1; Hao, Xiao-Jiang1
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| 2013-12-01 | |
| Source Publication | PHYTOCHEMISTRY
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| Volume | 96Pages:360-369 |
| Abstract | Sixteen daphnane diterpenoids, trigothysoids A-P, along with 15 known ones, were isolated from the methanol extract of the twigs and leaves of Trigonostemon thy rsoideum. Their structures were established by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. The anti-HIV-1 activity of the compounds was also evaluated in vitro, and five compounds demonstrated potent anti-HIV-1 activity, with EC50 values of 0.015-0.001 nM and TI values of 1618-17,619. (C) 2013 Elsevier Ltd. All rights reserved. |
| Keyword | Trigonostemon Thyrsoideum Euphorbiaceae Daphnane Diterpenoids Trigothysoids A-p Anti-hiv-1 |
| Indexed By | SCI ; IC |
| Language | 英语 |
| WOS ID | WOS:000328869500038 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/19233 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China |
| Recommended Citation GB/T 7714 | Cheng, Yuan-Yuan,Chen, Huan,He, Hong-Ping,et al. Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum[J]. PHYTOCHEMISTRY,2013,96:360-369. |
| APA | Cheng, Yuan-Yuan.,Chen, Huan.,He, Hong-Ping.,Zhang, Yu.,Li, Shi-Fei.,...&Hao, Xiao-Jiang.(2013).Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum.PHYTOCHEMISTRY,96,360-369. |
| MLA | Cheng, Yuan-Yuan,et al."Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum".PHYTOCHEMISTRY 96(2013):360-369. |
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| 1-s2.0-S003194221300（973KB） | 开放获取 | CC BY-NC-ND | View Download | |||
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