Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum

	Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum
	Cheng, Yuan-Yuan 1,2; Chen, Huan 2,3; He, Hong-Ping 1; Zhang, Yu1 ; Li, Shi-Fei 1,2; Tang, Gui-Hua1,2 ; Guo, Ling-Li1 ; Yang, Wei 1,2; Zhu, Feng 1,2; Zheng, Yong-Tang 3; Li, Shun-Lin 1; Hao, Xiao-Jiang1
	2013-12-01
发表期刊	PHYTOCHEMISTRY
卷号	96 页码:360-369
摘要	Sixteen daphnane diterpenoids, trigothysoids A-P, along with 15 known ones, were isolated from the methanol extract of the twigs and leaves of Trigonostemon thy rsoideum. Their structures were established by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. The anti-HIV-1 activity of the compounds was also evaluated in vitro, and five compounds demonstrated potent anti-HIV-1 activity, with EC50 values of 0.015-0.001 nM and TI values of 1618-17,619. (C) 2013 Elsevier Ltd. All rights reserved.
关键词	Trigonostemon Thyrsoideum Euphorbiaceae Daphnane Diterpenoids Trigothysoids A-p Anti-hiv-1
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000328869500038
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/19233
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Yuan-Yuan,Chen, Huan,He, Hong-Ping,et al. Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum[J]. PHYTOCHEMISTRY,2013,96:360-369.
APA	Cheng, Yuan-Yuan.,Chen, Huan.,He, Hong-Ping.,Zhang, Yu.,Li, Shi-Fei.,...&Hao, Xiao-Jiang.(2013).Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum.PHYTOCHEMISTRY,96,360-369.
MLA	Cheng, Yuan-Yuan,et al."Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum".PHYTOCHEMISTRY 96(2013):360-369.

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