A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud
Adelakun, Tiwalade A.1,2,3; Ding, Xiao1; Ombati, Rose M.2; Zhao, Ning-Dong1; Obodozie-Ofoegbu, Obiageri3; Di, Ying-Tong1; Zhang, Yu1; Hao, Xiao-Jiang1
Corresponding AuthorZhang, Yu(zhangyu@mail.kib.ac.cn) ; Hao, Xiao-Jiang(haoxj@mail.kib.ac.cn)
2019-05-07
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
Pages9
AbstractTwenty-two diterpenoids (1-22), including two new ones (1, a tigliane-type diterpenoid and 8, an abietane-type diterpenoid) were isolated from the roots of Euphorbia fischeriana Steud. Among them, compounds 4, 7, 12, 14-16, 19-21 are isolated from this plant for the first time. Their structures were elucidated through extensive 1D, 2D NMR and the HRESIMS data. The C-13 data of 4 is hereby presented for the first time. The macrocyclic diterpenes 1 and 2 showed marked enhancement of lysosomal biosynthesis after evaluation using lysoTracker staining method. [GRAPHICS] .
KeywordEuphorbia fischeriana Steud highly oxygenated abietanes phorbol esters lysosomal biogenesis
DOI10.1080/14786419.2019.1607331
Indexed BySCI
Language英语
WOS IDWOS:000469633400001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/67421
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorZhang, Yu; Hao, Xiao-Jiang
Affiliation1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.NIPRD, Med Chem & Qual Control Dept, Abuja, Nigeria
Recommended Citation
GB/T 7714
Adelakun, Tiwalade A.,Ding, Xiao,Ombati, Rose M.,et al. A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud[J]. NATURAL PRODUCT RESEARCH,2019:9.
APA Adelakun, Tiwalade A..,Ding, Xiao.,Ombati, Rose M..,Zhao, Ning-Dong.,Obodozie-Ofoegbu, Obiageri.,...&Hao, Xiao-Jiang.(2019).A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud.NATURAL PRODUCT RESEARCH,9.
MLA Adelakun, Tiwalade A.,et al."A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud".NATURAL PRODUCT RESEARCH (2019):9.
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