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Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
浏览  |  Adobe PDF(5829Kb)  |  收藏  |  浏览/下载：78/17  |  提交时间：2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET  
Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 673
作者:  Lu, Qin;  He, Yuanming;  Wang, Yuehu;  Gao, Li;  Zheng, Yunjing;  Zhang, Zubin;  Cao, Biyin;  Wang, Qi;  Mao, Xinliang;  Hu, Shaoyan
收藏  |  浏览/下载：256/0  |  提交时间：2018/07/30
Tspf  Rnf6/akt/mtor Signaling Pathway  Acute Myeloid Leukemia  Herbal Medicine  Saponins  Cell Apoptosis  Rnf6  
Elaborating the Role of Natural Products on the Regulation of Autophagy and their Potentials in Breast Cancer Therapy 期刊论文
CURRENT CANCER DRUG TARGETS, 2018, 卷号: 18, 期号: 3, 页码: 239-255
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Tsui, Stephen Kwok-Wing;  Pu, Jianxin;  Fung, Kwok-Pui;  Lau, Clara Bik-San
收藏  |  浏览/下载：135/0  |  提交时间：2018/05/08
Autophagy  Natural Products  Breast Cancer  Cancer Therapy  Mtor Signaling  Apoptosis  
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载：204/50  |  提交时间：2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
作者:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
浏览  |  Adobe PDF(1017Kb)  |  收藏  |  浏览/下载：371/63  |  提交时间：2017/02/14
Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：230/47  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 卷号: 35
作者:  Wang, Min;  Zhou, Ankun;  An, Tao;  Kong, Lingmei;  Yu, Chunlei;  Liu, Jianmei;  Xia, Chengfeng;  Zhou, Hongyu;  Li, Yan
浏览  |  Adobe PDF(1734Kb)  |  收藏  |  浏览/下载：326/63  |  提交时间：2016/06/27
N-hydroxyphthalimide  Mtor  Inhibitor  Cancer  Mitochondrial Apoptosis  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
浏览  |  Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：753/118  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Hitting the Golden TORget: Curcumin's Effects on mTOR Signaling 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 7, 页码: 988-994
作者:  Beevers, Christopher S.;  Zhou, Hongyu;  Huang, Shile
浏览  |  Adobe PDF(230Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2013/10/16
Curcumin  Mtor  Akt  Cancer  Cell Proliferation  Cell Death  
mTOR信号通路抑制剂筛选及抗肿瘤活性和机制研究 学位论文
, 北京: 中国科学院大学, 2013
作者:  闫居明
Adobe PDF(2112Kb)  |  收藏  |  浏览/下载：273/10  |  提交时间：2016/05/31
肿瘤  Mtor信号通路  天然产物  活性筛选  机制研究