Identification of two novel inhibitors of mTOR signaling pathway based on high content screening

	Identification of two novel inhibitors of mTOR signaling pathway based on high content screening
	Yan, Juming 1,2; Zhou, Hongyu 1; Kong, Lingmei 1,2; Zhang, Jing 1,2; Zhao, Qinshi1 ; Li, Yan1
通讯作者	Li, Y (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.,liyanb@mail.kib.ac.cn
	2013-10-01
发表期刊	CANCER CHEMOTHERAPY AND PHARMACOLOGY
ISSN	0344-5704
卷号	72 期号:4 页码:799-808
摘要	Mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in regulating cell growth, proliferation and survival. Dysregulation of mTOR signaling pathway is closely involved in cancer development and chemotherapy resistance. Inhibitors of mTOR signaling pathway have been demonstrated to be attractive therapeutics for cancer therapy. In the present study, we aim to discover novel mTOR signaling pathway inhibitors from a natural compound library.
关键词	Mtor Signaling Inhibitor High Content Screening Cancer Apoptosis
学科领域	Oncology ; Pharmacology & Pharmacy
收录类别	SCI
语种	英语
WOS记录号	WOS:000324879100009
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/17289
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Yan, Juming,Zhou, Hongyu,Kong, Lingmei,et al. Identification of two novel inhibitors of mTOR signaling pathway based on high content screening[J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY,2013,72(4):799-808.
APA	Yan, Juming,Zhou, Hongyu,Kong, Lingmei,Zhang, Jing,Zhao, Qinshi,&Li, Yan.(2013).Identification of two novel inhibitors of mTOR signaling pathway based on high content screening.CANCER CHEMOTHERAPY AND PHARMACOLOGY,72(4),799-808.
MLA	Yan, Juming,et al."Identification of two novel inhibitors of mTOR signaling pathway based on high content screening".CANCER CHEMOTHERAPY AND PHARMACOLOGY 72.4(2013):799-808.

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