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A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
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MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
Apigenin exerts chemopreventive effects on lung injury induced by SiO2 nanoparticles through the activation of Nrf2 期刊论文
JOURNAL OF NATURAL MEDICINES, 2022, 卷号: 76, 期号: 1, 页码: 119-131
Authors:  Wang,Yajun;  Chang,Wenhui;  Li,Xuezheng;  Jiang,Zhe;  Zhou,Di;  Feng,Yuan;  Li,Bingxin;  Chen,Gang;  Li,Ning
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APG  Lung injury  Nm SiO2  Nrf2  Chemoprevention  OCCUPATIONAL SILICA EXPOSURE  OXIDATIVE STRESS  PARTICULATE MATTER  INDUCED APOPTOSIS  CELL-LINE  CANCER  PROTECTS  NEUROPROTECTION  INFLAMMATION  TOXICITY  
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
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Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Noncoding RNAs and RNA-binding proteins in diabetic wound healing 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 50, 页码: 128311
Authors:  Li,Xue;  Li,Ning;  Li,Bingxin;  Feng,Yuan;  Zhou,Di;  Chen,Gang
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ncRNAs  lncRNAs  circRNAs  RNA-binding protein  Modulating drugs  Diabetic  Wound healing  ENDOTHELIAL-CELLS  OXIDATIVE STRESS  PROLIFERATION  APOPTOSIS  INFLAMMATION  DYSFUNCTION  EXPRESSION  MIGRATION  CANCER  INJURY  
Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112656
Authors:  Kaunda,Joseph Sakah;  Qin,Xu-Jie;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Solanum violaceum  Solanaceae  Glycoalkaloids  Solanindiosides A-C  235,26R-hydroxylated spirostanoid saponin  Lignans  Cytotoxicity  Apoptosis  Antibacterial  Staphylococcus aureus  
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell 期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
Authors:  He,YingYing;  He,Zhicheng;  Lin,Jian;  Chen,Cheng;  Chen,Yuanzhi;  Liu,Shubai
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BINDING-PROTEIN CTBP  TRANSCRIPTIONAL COREPRESSOR  NEGATIVE MODULATION  PROMOTES APOPTOSIS  GENE-EXPRESSION  DAMAGE RESPONSE  PK  OVEREXPRESSION  PHOSPHOPROTEIN  TRANSFORMATION  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Optimization of extraction process and antioxidant activities of saponins from Camelliafascicularis leaves 期刊论文
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, 2021, 卷号: 15, 期号: 2, 页码: 1889-1898
Authors:  Hu,Xiang;  Tang,Jun-rong;  Zhang,Gui-liang;  Deng,Jia;  Kan,Huan;  Zhang,Ying-jun;  Zhao,Ping;  Liu,Yun
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Camelliafascicularis chang  Saponins  Ultrasonic-assisted extraction  Box  Behnken design  Antioxidant activity  ULTRASONIC-ASSISTED EXTRACTION  CHEMICAL-CONSTITUENTS  CAMELLIA-NITIDISSIMA  PANAX-GINSENG  POLYSACCHARIDES  GINSENOSIDES  COMPONENTS  INDUCTION  APOPTOSIS  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
Authors:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
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Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
Antimicrobial Peptide Brevivin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 2059
Authors:  Ju,Xiaoman;  Fan,Dongmei;  Kong,Lingmei;  Yang,Qihong;  Zhu,Yiying;  Zhang,Shaohua;  Su,Guifeng;  Li,Yan
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antimicrobial peptide  Brevivin-1RL1  apoptosis  necrosis  caspase  anticancer  BULLFROG  PHOSPHATIDYLSERINE  MECHANISMS  ANTITUMOR  SURFACE