Horizontally acquired fungal killer protein genes affect cell development in mosses

doi:10.1111/tpj.16060

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	Horizontally acquired fungal killer protein genes affect cell development in mosses
	Guan,Yanlong; Ma,Lan; Wang,Qia; Zhao,Jinjie; Wang,Shuanghua; Wu,Jinsong; Liu,Yang; Sun,Hang; Huang,Jinling
	2023
发表期刊	PLANT JOURNAL
ISSN	1365-313X
摘要	The moss Physcomitrium patens is crucial for studying plant development and evolution. Although the P. patens genome includes genes acquired from bacteria, fungi and viruses, the functions and evolutionary significance of these acquired genes remain largely unclear. Killer protein 4 (KP4) is a well-studied toxin secreted by ascomycete fungi, such as the corn smut Ustilago maydis, which inhibits the growth of sensitive target strains by blocking their calcium uptake. Here, we show that KP4 genes in mosses were acquired from fungi through at least three independent events of horizontal gene transfer. Two paralogous copies of KP4 (PpKP4-1 and PpKP4-2) exist in P. patens. Knockout mutants ppkp4-1 and ppkp4-2 showed cell death at the protonemal stage, and ppkp4-2 also exhibited defects in tip growth. We provide experimental evidence indicating that PpKP4-1/2 affects P. patens protonemal cell development by mediating cytoplasmic calcium and that KP4 genes are functionally conserved between P. patens and fungi. The present study provides additional insights into the role of horizontal gene transfer in land plant development and evolution.
关键词	horizontal gene transfer Physcomitrium patens killer protein 4 plant evolution cytoplasmic calcium cell death PHYSCOMITRELLA-PATENS CALCIUM-CHANNELS USTILAGO-MAYDIS PLANT LAND GROWTH TOXIN APOPTOSIS INSIGHTS GENOMES
学科领域	Plant Sciences
DOI	10.1111/tpj.16060
收录类别	SCI
WOS记录号	WOS:000911185000001
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75250
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Guan,Yanlong,Ma,Lan,Wang,Qia,et al. Horizontally acquired fungal killer protein genes affect cell development in mosses[J]. PLANT JOURNAL,2023.
APA	Guan,Yanlong.,Ma,Lan.,Wang,Qia.,Zhao,Jinjie.,Wang,Shuanghua.,...&Huang,Jinling.(2023).Horizontally acquired fungal killer protein genes affect cell development in mosses.PLANT JOURNAL.
MLA	Guan,Yanlong,et al."Horizontally acquired fungal killer protein genes affect cell development in mosses".PLANT JOURNAL (2023).

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