| Identification of two novel inhibitors of mTOR signaling pathway based on high content screening | |
Yan, Juming1,2; Zhou, Hongyu1; Kong, Lingmei1,2; Zhang, Jing1,2; Zhao, Qinshi1 ; Li, Yan1
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| 通讯作者 | Li, Y (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.,liyanb@mail.kib.ac.cn |
| 2013-10-01 | |
| 发表期刊 | CANCER CHEMOTHERAPY AND PHARMACOLOGY
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| ISSN | 0344-5704 |
| 卷号 | 72期号:4页码:799-808 |
| 摘要 | Mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in regulating cell growth, proliferation and survival. Dysregulation of mTOR signaling pathway is closely involved in cancer development and chemotherapy resistance. Inhibitors of mTOR signaling pathway have been demonstrated to be attractive therapeutics for cancer therapy. In the present study, we aim to discover novel mTOR signaling pathway inhibitors from a natural compound library. |
| 关键词 | Mtor Signaling Inhibitor High Content Screening Cancer Apoptosis |
| 学科领域 | Oncology ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000324879100009 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/17289 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Juming,Zhou, Hongyu,Kong, Lingmei,et al. Identification of two novel inhibitors of mTOR signaling pathway based on high content screening[J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY,2013,72(4):799-808. |
| APA | Yan, Juming,Zhou, Hongyu,Kong, Lingmei,Zhang, Jing,Zhao, Qinshi,&Li, Yan.(2013).Identification of two novel inhibitors of mTOR signaling pathway based on high content screening.CANCER CHEMOTHERAPY AND PHARMACOLOGY,72(4),799-808. |
| MLA | Yan, Juming,et al."Identification of two novel inhibitors of mTOR signaling pathway based on high content screening".CANCER CHEMOTHERAPY AND PHARMACOLOGY 72.4(2013):799-808. |
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| Yan-2013-Identificat（1971KB） | 开放获取 | CC BY-NC-SA | 浏览 下载 | |||
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