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Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:  Dong,Wei;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Li,Tian-Ze;  Wang,Yong-Cui;  He,Xiao-Feng;  Geng,Chang-An;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(3816Kb)  |  收藏  |  浏览/下载：53/15  |  提交时间：2024/07/10
Artemzhongdianolides B1-B17  Artemisia zhongdianensis  Guaiane-type sesquiterpenoid dimers  Antihepatoma activity  p38MAPK pathway  Cancer  NMR spectroscopy  X-ray diffraction  ARREST  CELLS  JNK  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(16654Kb)  |  收藏  |  浏览/下载：62/7  |  提交时间：2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
浏览  |  Adobe PDF(29350Kb)  |  收藏  |  浏览/下载：37/5  |  提交时间：2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
作者:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(1447Kb)  |  收藏  |  浏览/下载：89/14  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
Association of sirtuins (SIRT1-7) with lung and intestinal diseases 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2022, 卷号: 477, 期号: 11, 页码: 2539-2552
作者:  Chen, Yuhan;  Zhou, Di;  Feng, Yuan;  Li, Bingxin;  Cui, Yong;  Chen, Gang;  Li, Ning
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：94/14  |  提交时间：2024/04/30
Sirtuins  Lung-intestinal axis  Inflammation  Tumors  MicroRNAs  ENDOPLASMIC-RETICULUM STRESS  EPITHELIAL-MESENCHYMAL TRANSITION  CANCER CELLS  ULCERATIVE-COLITIS  COLORECTAL-CANCER  DOWN-REGULATION  PROLIFERATION  SUPPRESSES  ACTIVATION  APOPTOSIS  
Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment 期刊论文
BIOMEDICINES, 2022, 卷号: 10, 期号: 11, 页码: 2841
作者:  He, Zhicheng;  Lin, Jian;  He, Yingying;  Liu, Shubai
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Trametes versicolor  polysaccharide peptide  colorectal cancer  traditional medicine  PROTEIN-BOUND POLYSACCHARIDE  QUEL PS-K  CORIOLUS-VERSICOLOR  IN-VITRO  ANTICANCER ACTIVITY  SIGNALING PATHWAY  ANTITUMOR  CELLS  MUSHROOM  COMBINATION  
Anti-Inflammatory Effects of Camellia fascicularis Polyphenols via Attenuation of NF-kappa B and MAPK Pathways in LPS-Induced THP-1 Macrophages 期刊论文
JOURNAL OF INFLAMMATION RESEARCH, 2022, 卷号: 15, 页码: 851-864
作者:  Gao, Miaozi;  Peng, Xiaowei;  Tang, Junrong;  Deng, Jia;  Wang, Fang;  Zhang, Yingjun;  Zhao, Ping;  Kan, Huan;  Liu, Yun
浏览  |  Adobe PDF(9145Kb)  |  收藏  |  浏览/下载：101/27  |  提交时间：2024/04/30
Camellia fascicularis  polyphenols  anti-inflammatory activity  NF-kappa B  MAPK  LIPOPOLYSACCHARIDE-INDUCED INFLAMMATION  OXIDATIVE STRESS  CELLS  SUPPRESSION  ANTIOXIDANT  ACTIVATION  NRF2/HO-1  RESPONSES  PROTEIN  CANCER  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载：105/19  |  提交时间：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Polyphyllin I combined with doxorubicin shows chemosensitization effect in vivo and reduces immunotoxicity of doxorubicin 期刊论文
MOLECULAR & CELLULAR TOXICOLOGY, 2022, 卷号: 18, 期号: 3, 页码: 359-369
作者:  Zhu, Xiang;  Na, Xin;  Zeng, Yueqin;  Xu, Yangantai;  Chai, Dongya;  Yang, Huanzhi;  Miao, Jingqian;  Zhang, Yuan;  Yang, Fenghua;  Wang, Yuehu;  Zhou, Yiping
浏览  |  Adobe PDF(1889Kb)  |  收藏  |  浏览/下载：73/12  |  提交时间：2024/04/30
Polyphyllin I  Chemosensitization  Doxorubicin  Immunotoxicity  Hemolysis  BREAST-CANCER CELLS  SAPONIN  INHIBITION  RESISTANCE  CISPLATIN  
Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression 期刊论文
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 卷号: 21, 期号: 1, 页码: e123909
作者:  Lin Jian;  He Zhicheng;  Liu Shubai
浏览  |  Adobe PDF(3879Kb)  |  收藏  |  浏览/下载：33/2  |  提交时间：2024/08/21
Colorectal Cancer  Trametes Versicolor  EGFR  PD-L1  Polysaccharide Peptide  CORIOLUS-VERSICOLOR  SIGNALING PATHWAY  COLON-CANCER  T-CELLS  STATISTICS  THERAPY