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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：115/15  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
浏览  |  Adobe PDF(11543Kb)  |  收藏  |  浏览/下载：112/16  |  提交时间：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L. 期刊论文
TETRAHEDRON LETTERS, 2023, 卷号: 123, 页码: 154550
作者:  Huang,Jian-Yi;  Yang,Ying;  Liang,Hong;  Pu,Xue-Xue;  Li,Ying-Yao;  Cai,Min;  Guo,Feng;  Liu,Lin;  Cao,Ming-Ming;  Yan,Ying;  Cheng,Yuanyuan;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(767Kb)  |  收藏  |  浏览/下载：106/22  |  提交时间：2024/07/17
Anti-inflammatory  Pepluane  Diterpenoid  Euphorbia peplus L  Chemical transformation  DISCOVERY  PARALIANE  INSIGHTS  PROFILE  LATEX  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
浏览  |  Adobe PDF(25423Kb)  |  收藏  |  浏览/下载：132/30  |  提交时间：2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 16196
作者:  Cai,Min;  Bai,Xiao-Lin;  Zang,Hao-Jing;  Tang,Xiao-Han;  Yan,Ying;  Wan,Jia-Jia;  Peng,Min-You;  Liang,Hong;  Liu,Lin;  Guo,Feng;  Zhao,Pei-Ji;  Liao,Xun;  Di,Ying-Tong;  Hao,Xiao-Jiang
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Harrisonia perforata  quassinoid  simarubaceae  neuroprotection  PC12 cells  PINK1(B9) flies  PROMISING BIOLOGICAL-ACTIVITY  UNPRECEDENTED QUASSINOIDS  
seco-Prezizanne Sesquiterpenes and Prenylated C6-C3 Compounds from the Fruits of Illicium lanceolatum A. C. Smith 期刊论文
CHEMISTRY & BIODIVERSITY, 2022, 卷号: 19, 期号: 1, 页码: e202100868
作者:  Nie,Wei;  Ding,Lin-Fen;  Tie-Lei;  Zhou,Hao-Feng;  Bao,Yi;  Song,Liu-Dong;  Pan,Zheng-Hong;  Wu,Xing-De;  Zhao,Qin-Shi
浏览  |  Adobe PDF(1850Kb)  |  收藏  |  浏览/下载：291/84  |  提交时间：2022/04/02
Illicium lanceolatum A  C  Smith  seco-prezizanne sesquiterpene  prenylated C6-C3 compound  neuroprotective activity  NEUROTROPHIC ACTIVITY  C-6-C-3 COMPOUNDS  STEM BARK  ROOTS  SKELETON  
A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses 期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2022, 卷号: 20, 期号: 1, 页码: 320
作者:  Chen, Sisi;  Yang, Liu;  Ou, Xia;  Li, Jin-Yu;  Zi, Cheng-Ting;  Wang, Hao;  Hu, Jiang-Miao;  Liu, Ye
浏览  |  Adobe PDF(7638Kb)  |  收藏  |  浏览/下载：80/23  |  提交时间：2024/04/30
Polysaccharide  Self-adjuvant  Nanovaccine  SARS-CoV-2  HIV  STRUCTURAL-CHARACTERIZATION  DENDRITIC CELLS  DRUG-DELIVERY  NANOPARTICLES  PARTICLES  CHITOSAN  GLYCOGEN  DESIGN  
Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa 期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 14, 页码: 4464
作者:  Yu, Hang;  Li, Jinliang;  Wu, Guoxing;  Tang, Qingbo;  Duan, Xiuan;  Liu, Quanjun;  Lan, Mingxian;  Zhao, Yuhan;  Hao, Xiaojiang;  Qin, Xiaoping;  Ding, Xiao
浏览  |  Adobe PDF(2365Kb)  |  收藏  |  浏览/下载：88/17  |  提交时间：2024/04/30
antifeedant  Dodonaea viscosa  Spodoptera litura  taste sensillum  GABA  detoxification enzyme  LITURA LEPIDOPTERA-NOCTUIDAE  SENSORY RESPONSES  FIELD  
Fire-prone Rhamnaceae with South African affinities in Cretaceous Myanmar amber 期刊论文
NATURE PLANTS, 2022, 卷号: 8, 期号: 2, 页码: 125-135
作者:  Shi, Chao;  Wang, Shuo;  Cai, Hao-Hong;  Zhang, Hong-Rui;  Long, Xiao-Xuan;  Tihelka, Erik;  Song, Wei-cai;  Feng, Qi;  Jiang, Ri-xin;  Cai, Chen-Yang;  Lombard, Natasha;  Li, Xiong;  Yuan, Ji;  Zhu, Jian-ping;  Yang, Hui-yu;  Liu, Xiao-fan;  Xiang, Qiao-ping;  Zhao, Zun-tian;  Long, Chun-lin;  Schneider, Harald;  Zhang, Xian-chun;  Peng, Hua;  Li, De-Zhu;  Fan, Yong;  Engel, Michael S.;  Wang, Yong-Dong;  Spicer, Robert A.
浏览  |  Adobe PDF(1521Kb)  |  收藏  |  浏览/下载：197/37  |  提交时间：2024/03/11
Three new jatrophane diterpenoids from Euphorbia peplus Linn. with activity towards autophagic flux 期刊论文
PHYTOCHEMISTRY LETTERS, 2022, 卷号: 50, 页码: 141-146
作者:  Pu, Xue-Xue;  Ran, Xiao-Qian;  Yan, Ying;  Lu, Qing-Yun;  Li, Jin-Cun;  Li, Ying-Yao;  Guan, Shi-Peng;  Cao, Ming-Ming;  Liu, Jie;  Hao, Xiao-Jiang;  Luo, Rong-Can;  Di, Ying-Tong
浏览  |  Adobe PDF(1310Kb)  |  收藏  |  浏览/下载：213/47  |  提交时间：2024/03/11