Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa

doi:10.3390/molecules27144464

KIB OpenIR

	Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa
	Yu, Hang; Li, Jinliang; Wu, Guoxing; Tang, Qingbo; Duan, Xiuan; Liu, Quanjun; Lan, Mingxian; Zhao, Yuhan; Hao, Xiaojiang; Qin, Xiaoping; Ding, Xiao
	2022
发表期刊	MOLECULES
卷号	27 期号:14 页码:4464
摘要	Dodonaea viscosa is a medicinal plant which has been used to treat various diseases in humans. However, the anti-insect activity of extracts from D. viscosa has not been evaluated. Here, we found that the total saponins from D. viscosa (TSDV) had strong antifeedant and growth inhibition activities against 4th-instar larvae of Spodoptera litura. The median antifeeding concentration (AFC(50)) value of TSDV on larvae was 1621.81 mu g/mL. TSDV affected the detoxification enzyme system of the larvae and also exerted antifeedant activity possibly through targeting the gamma-aminobutyric acid (GABA) system. The AFC(50) concentration, the carboxylesterase activity, glutathione S-transferases activity, and cytochrome P450 content increased to 258%, 205%, and 215%, respectively, and likewise the glutamate decarboxylase activity and GABA content to 195% and 230%, respectively, in larvae which fed on TSDV. However, D. viscosa saponin A (DVSA) showed better antifeedant activity and growth inhibition activity in larvae, compared to TSDV. DVSA also exerted their antifeedant activity possibly through targeting the GABA system and subsequently affected the detoxification enzyme system. Further, DVSA directly affected the medial sensillum and the lateral sensillum of the 4th-instar larvae. Stimulation of Spodoptera litura. with DVSA elicited clear, consistent, and robust excitatory responses in a single taste cell.
关键词	antifeedant Dodonaea viscosa Spodoptera litura taste sensillum GABA detoxification enzyme LITURA LEPIDOPTERA-NOCTUIDAE SENSORY RESPONSES FIELD
DOI	10.3390/molecules27144464
收录类别	SCI
WOS记录号	WOS:000833603700001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/74682
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Yu, Hang,Li, Jinliang,Wu, Guoxing,et al. Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa[J]. MOLECULES,2022,27(14):4464.
APA	Yu, Hang.,Li, Jinliang.,Wu, Guoxing.,Tang, Qingbo.,Duan, Xiuan.,...&Ding, Xiao.(2022).Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa.MOLECULES,27(14),4464.
MLA	Yu, Hang,et al."Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa".MOLECULES 27.14(2022):4464.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
ARTN 4464.pdf（2365KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览下载