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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：288/1  |  提交时间：2017/07/24
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
作者:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  收藏  |  浏览/下载：176/1  |  提交时间：2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Effects of CO-RM2 on LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  Pei-Ling Chi;  Yu-Chen Chuang;  Yu-Wen Chen;  Chih-Chung Lin;  Li-Der Hsiao;  Chuen-Mao Yang
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：182/1  |  提交时间：2017/07/24
Carbon Monoxide  Lipopolysaccharide  Vcam-1  Leukocyte Adhesion  
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
作者:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
Adobe PDF(4722Kb)  |  收藏  |  浏览/下载：153/42  |  提交时间：2022/04/02
Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：104/14  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Milk Exosomes Transfer Oligosaccharides into Macrophages to Modulate Immunity and Attenuate Adherent-Invasive E. coli (AIEC) Infection 期刊论文
NUTRIENTS, 2021, 卷号: 13, 期号: 9, 页码: 3198
作者:  He,Yingying;  He,Zhicheng;  Leone,Serena;  Liu,Shubai
浏览  |  Adobe PDF(4239Kb)  |  收藏  |  浏览/下载：91/13  |  提交时间：2022/04/02
HMOs  exosome  mucosal immunity  2 '-FL  macrophages  INTESTINAL HOMEOSTASIS  MECHANISM  VESICLES  RECEPTOR  CELLS  
Antifeedant, cytotoxic, and anti-inflammatory neo-clerodane diterpenoids in the peltate glandular trichomes and fresh leaves of Ajuga forrestii 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 186, 页码: 112731
作者:  Wang,Ying;  Liu,Yan-Chun;  Li,Wen-Yuan;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(4803Kb)  |  收藏  |  浏览/下载：77/24  |  提交时间：2022/04/02
Ajuga forrestii Diels  Lamiaceae  Glandular trichomes  Laser microdissection  Diterpenoids  Defensive function  Antifeedant activity  Anti-inflammatory activity  Cytotoxicity  SESQUITERPENE LACTONES  PHYTOCHEMISTRY  CONSTITUENTS  DECUMBENS  HARBOR  PLANTS  L.  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
作者:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
Adobe PDF(2177Kb)  |  收藏  |  浏览/下载：116/57  |  提交时间：2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
Adobe PDF(1847Kb)  |  收藏  |  浏览/下载：64/15  |  提交时间：2022/04/02
Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT  
Multiple in vitro biological effects of phenolic compounds from Terminalia chebula var. tomentella 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 275, 页码: 114135
作者:  Zhang,Xiao-Rui;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Kong,Qing-Hua;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
Adobe PDF(2686Kb)  |  收藏  |  浏览/下载：131/26  |  提交时间：2022/04/02
Terminalia chebula var  tomentella  Combretaceae  Fructus Chebulae  Hydrolyzed tannins  Simple phenolic compounds  Anti-inflammation  Anti-diabetes  NITRIC-OXIDE  ANTIOXIDANT  TANNINS  CONSTITUENTS  VALIDATION  ALGORITHM  ESTERS  FRUITS