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Structure and heparanase inhibitory activity of a new glycosaminoglycan from the slug Limacus flavus 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 220, 页码: 176-184
作者:  He, Zhicheng;  Zhou, Lutan;  Lin, Lisha;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(1875Kb)  |  收藏  |  浏览/下载：190/29  |  提交时间：2019/07/29
Slug  Glycosaminoglycan  Chemical structure  Depolymerization  Heparanase inhibition  
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：294/154  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
Mangiterpenes A-C and 2 ',3 '-seco-manginoid C, four sesquiterpene/monoterpene-shikimate-conjugated spirocyclic meroterpenoids from Guignardia mangiferae 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 236-242
作者:  Chen, Keliang;  Chen, Chunmei;  Guo, Jieru;  Sun, Weiguang;  Liu, Junjun;  Yang, Jing;  Liu, Xiulan;  Wang, Jianping;  Luo, Zengwei;  Zhu, Hucheng;  Zhang, Yonghui
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Guignardia Mangiferae  Spirocyclic Meroterpenoids  Anti-inflammatory  Nuclear Factor-kappa b (Nf-kappa b)  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
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Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1837Kb)  |  收藏  |  浏览/下载：207/37  |  提交时间：2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：310/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
作者:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
浏览  |  Adobe PDF(1287Kb)  |  收藏  |  浏览/下载：241/58  |  提交时间：2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：213/55  |  提交时间：2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
Site-specific peak intensity ratio (SPIR) from 1D H-2/H-1 NMR spectra for rapid distinction between natural and synthetic nicotine and detection of possible adulteration 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 24, 页码: 6427-6434
作者:  Liu,Bin;  Chen,Yanli;  Ma,Xiaofang;  Hu,Kaifeng
浏览  |  Adobe PDF(494Kb)  |  收藏  |  浏览/下载：162/73  |  提交时间：2020/04/02