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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
Authors:
Dai, Manyun
;
Peng, Wan
;
Zhang, Ting
;
Zhao, Qi
;
Ma, Xiaofang
;
Cheng, Yan
;
Wang, Chunyan
;
Li, Fei
Favorite
  |  
View/Download:17/0
  |  
Submit date:2022/07/15
Tripterygium wilfordii
Liver injury
PPAR alpha
IL6-STAT3
Metabolomics
PXR mediates mifepristone-induced hepatomegaly in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:
Yao,Xin-peng
;
Jiao,Ting-ying
;
Jiang,Yi-ming
;
Fan,Shi-cheng
;
Zhao,Ying-yuan
;
Yang,Xiao
;
Gao,Yue
;
Li,Fei
;
Zhou,Yan-ying
;
Chen,Pan-pan
;
Huang,Min
;
Bi,Hui-chang
Favorite
  |  
View/Download:3/0
  |  
Submit date:2022/04/02
mifepristone
hepatomegaly
pregnane X receptor (PXR)
yes-associated protein (YAP)
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
Favorite
  |  
View/Download:10/0
  |  
Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:
Dai,Zhi
;
Liu,Hui
;
Wang,Bei
;
Yang,Dong
;
Zhu,Yan-Yan
;
Yan,Huan
;
Zhu,Pei-Feng
;
Liu,Ya-Ping
;
Chen,Hui-Cheng
;
Zhao,Yun-li
;
Zhao,Li-Xing
;
Zhao,Xu-Dong
;
Liu,Hai-Yang
;
Luo,Xiao-Dong
Favorite
  |  
View/Download:8/0
  |  
Submit date:2022/04/02
Steroidal saponins
Structure-activity relationship
Tribulosaponin A
Glioma stem cells
ROS
SMALL MOLECULES
CARDIAC-ARREST
STEM-CELL
IDENTIFICATION
THERAPY
BRAIN
OPPORTUNITIES
GLIOMA
TUMORS
NOX2
Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443
Authors:
Zhang,Quanwei
;
Liu,Man
;
Li,Lifeng
;
Chen,Miaomiao
;
Puno,Pema Tenzin
;
Bao,Wanrong
;
Zheng,Hongming
;
Wen,Xin
;
Cheng,Huiyuan
;
Fung,Hauyee
;
Wong,Tinlong
;
Zhao,Zhongzhen
;
Lyu,Aiping
;
Han,Quanbin
;
Sun,Handong
Favorite
  |  
View/Download:4/0
  |  
Submit date:2022/04/02
Cordyceps
Polysaccharide
TLR4
MyD88
p38
Immune responses
Macrophage
NF-KAPPA-B
STRUCTURAL-CHARACTERIZATION
ANTIOXIDANT ACTIVITY
MYCELIAL FERMENTATION
SIGNALING PATHWAYS
FRUITING BODIES
SINENSIS FUNGUS
GENE-EXPRESSION
LIPOPOLYSACCHARIDE
RECOGNITION
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
Authors:
Zhu,Pei-Feng
;
Cheng,Gui-Guang
;
Zhao,Lan-Qin
;
Khan,Afsar
;
Yang,Xing-Wei
;
Zhang,Bu-Yun
;
Li,Meng-Cheng
;
Liu,Ya-Ping
;
Luo,Xiao-Dong
Favorite
  |  
View/Download:9/0
  |  
Submit date:2022/04/02
Rhynchanthus beesianus
diarylheptanoid
antioxidant activity
intracellular reactive oxygen species
cell apoptosis
GINGER ZINGIBER-OFFICINALE
PC12 CELLS
RHIZOMES
NEUROPROTECTION
ACTIVATION
ENZYMES
L.
Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells
期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 5, 页码: 757-762
Authors:
Dong,Fa-Wu
;
Li,Fang
;
Ren,Jia-Jia
;
Zhao,Cheng-Mei
;
Diao,Hong-Li
;
Li,Bao-Jing
;
Li,Yan-Ping
;
Hu,Jiang-Miao
;
He,Hong-Ping
Favorite
  |  
View/Download:6/0
  |  
Submit date:2022/04/02
Valeriana amurensis
sesquiterpenoids
central nervous system
PC12 cells
NERVE GROWTH-FACTOR
IRIDOID GLYCOSIDES
Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111107
Authors:
Wang,Yajie
;
Tan,Jiabin
;
Hu,Peng
;
Pei,Qiang
;
Wen,Yan
;
Ma,Wenqing
;
Shi,Keqian
;
Li,Zengzheng
;
Li,Huiyuan
;
Cheng,Fengyu
;
Gu,Xuezhong
;
Yao,Xiangmei
;
Man,Yan
;
Zhao,Renbin
;
Feng,Shuai
;
Ding,Xiao
;
Yang,Tonghua
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  |  
View/Download:4/0
  |  
Submit date:2022/04/02
Bu Shen Hui Yang Fang (BSHY)
Immunoenhancement
Lymphocytes
Proliferation
Cytokine
IL-4
ACUTE MYELOID-LEUKEMIA
IMMUNE-SYSTEM
CANCER
CELLS
IMMUNOSURVEILLANCE
EXPRESSION
A specific and bioactive polysaccharide marker for Cordyceps
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343
Authors:
Li,Li-Feng
;
But,Grace Wing-Chiu
;
Zhang,Quan-Wei
;
Liu,Man
;
Chen,Miao-Miao
;
Wen,Xin
;
Wu,Hoi-Yan
;
Cheng,Hui-Yuan
;
Puno,Pema-Tenzin
;
Zhang,Ji-Xia
;
Fung,Hau-Yee
;
Bai,Su-Ping
;
Wong,Tin-Long
;
Zhao,Zhong-Zhen
;
Cao,Hui
;
Tsim,Karl Wah-Keung
;
Shaw,Pang-Chui
;
Han,Quan-Bin
;
Sun,Han-Dong
Favorite
  |  
View/Download:3/0
  |  
Submit date:2022/04/02
Cordyceps
Polysaccharide
Marker
Authentication
Immune activity
STRUCTURAL-ANALYSIS
SINENSIS
AUTHENTICATION
MACROPHAGES
SEQUENCE
Polyamine metabolism links gut microbiota and testicular dysfunction
期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:
Zhao,Qi
;
Huang,Jian-Feng
;
Cheng,Yan
;
Dai,Man-Yun
;
Zhu,Wei-Feng
;
Yang,Xiu-Wei
;
Gonzalez,Frank J.
;
Li,Fei
Favorite
  |  
View/Download:3/0
  |  
Submit date:2022/04/02
Testicular dysfunction
Gut microbiota
Polyamine metabolism
Metabolomics
SMALL-MOLECULE INHIBITOR
ORNITHINE-DECARBOXYLASE
TRIPTOLIDE
SPERMINE
ACTIVATION
DISRUPTION
MECHANISMS
EXPRESSION
APOPTOSIS
TRANSPORT