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Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
Authors:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
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Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
Favorite  |  View/Download:3/0  |  Submit date:2022/04/02
mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443
Authors:  Zhang,Quanwei;  Liu,Man;  Li,Lifeng;  Chen,Miaomiao;  Puno,Pema Tenzin;  Bao,Wanrong;  Zheng,Hongming;  Wen,Xin;  Cheng,Huiyuan;  Fung,Hauyee;  Wong,Tinlong;  Zhao,Zhongzhen;  Lyu,Aiping;  Han,Quanbin;  Sun,Handong
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Cordyceps  Polysaccharide  TLR4  MyD88  p38  Immune responses  Macrophage  NF-KAPPA-B  STRUCTURAL-CHARACTERIZATION  ANTIOXIDANT ACTIVITY  MYCELIAL FERMENTATION  SIGNALING PATHWAYS  FRUITING BODIES  SINENSIS FUNGUS  GENE-EXPRESSION  LIPOPOLYSACCHARIDE  RECOGNITION  
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
Authors:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
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Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 5, 页码: 757-762
Authors:  Dong,Fa-Wu;  Li,Fang;  Ren,Jia-Jia;  Zhao,Cheng-Mei;  Diao,Hong-Li;  Li,Bao-Jing;  Li,Yan-Ping;  Hu,Jiang-Miao;  He,Hong-Ping
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Valeriana amurensis  sesquiterpenoids  central nervous system  PC12 cells  NERVE GROWTH-FACTOR  IRIDOID GLYCOSIDES  
Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111107
Authors:  Wang,Yajie;  Tan,Jiabin;  Hu,Peng;  Pei,Qiang;  Wen,Yan;  Ma,Wenqing;  Shi,Keqian;  Li,Zengzheng;  Li,Huiyuan;  Cheng,Fengyu;  Gu,Xuezhong;  Yao,Xiangmei;  Man,Yan;  Zhao,Renbin;  Feng,Shuai;  Ding,Xiao;  Yang,Tonghua
Favorite  |  View/Download:4/0  |  Submit date:2022/04/02
Bu Shen Hui Yang Fang (BSHY)  Immunoenhancement  Lymphocytes  Proliferation  Cytokine  IL-4  ACUTE MYELOID-LEUKEMIA  IMMUNE-SYSTEM  CANCER  CELLS  IMMUNOSURVEILLANCE  EXPRESSION  
A specific and bioactive polysaccharide marker for Cordyceps 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343
Authors:  Li,Li-Feng;  But,Grace Wing-Chiu;  Zhang,Quan-Wei;  Liu,Man;  Chen,Miao-Miao;  Wen,Xin;  Wu,Hoi-Yan;  Cheng,Hui-Yuan;  Puno,Pema-Tenzin;  Zhang,Ji-Xia;  Fung,Hau-Yee;  Bai,Su-Ping;  Wong,Tin-Long;  Zhao,Zhong-Zhen;  Cao,Hui;  Tsim,Karl Wah-Keung;  Shaw,Pang-Chui;  Han,Quan-Bin;  Sun,Han-Dong
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Cordyceps  Polysaccharide  Marker  Authentication  Immune activity  STRUCTURAL-ANALYSIS  SINENSIS  AUTHENTICATION  MACROPHAGES  SEQUENCE  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
Favorite  |  View/Download:3/0  |  Submit date:2022/04/02
Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT