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Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443
Authors:  Zhang,Quanwei;  Liu,Man;  Li,Lifeng;  Chen,Miaomiao;  Puno,Pema Tenzin;  Bao,Wanrong;  Zheng,Hongming;  Wen,Xin;  Cheng,Huiyuan;  Fung,Hauyee;  Wong,Tinlong;  Zhao,Zhongzhen;  Lyu,Aiping;  Han,Quanbin;  Sun,Handong
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Cordyceps  Polysaccharide  TLR4  MyD88  p38  Immune responses  Macrophage  NF-KAPPA-B  STRUCTURAL-CHARACTERIZATION  ANTIOXIDANT ACTIVITY  MYCELIAL FERMENTATION  SIGNALING PATHWAYS  FRUITING BODIES  SINENSIS FUNGUS  GENE-EXPRESSION  LIPOPOLYSACCHARIDE  RECOGNITION  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
Authors:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
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Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
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Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT  
Leucoabietenes A and B, rearranged abietane and ent-abietane diterpene hydrocarbons against resistant infectious fungus and bacterium from the leaves of Leucosceptrum canum 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 81, 页码: 153356
Authors:  Zhang,Man-Wen;  Guo,Kai;  Zhang,Yu;  Teng,Lin-Lin;  Huang,Qing-Pu;  Liu,Yan;  Li,Sheng-Hong
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Leucosceptrum canum  Ent-abietane diterpene  Abietane diterpene  Antimicrobial activity  TERPENOIDS  
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
Authors:  Wang,Yi-Kun;  Zhou,Zi-Meng;  Dai,Man-Yun;  Ma,Xiao-Fang;  Xiao,Xue-Rong;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
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Fructus Aurantii  quality markers  metabolomics  serum pharmacochemistry  ultra high performance liquid chromatography  SERUM PHARMACOCHEMISTRY  RAT PLASMA  IDENTIFICATION  METABOLITES  IMMATURUS  COMPONENTS  EXTRACT  NEOHESPERIDIN  FINGERPRINT  NARINGIN  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
Authors:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
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Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
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enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
A specific and bioactive polysaccharide marker for Cordyceps 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343
Authors:  Li,Li-Feng;  But,Grace Wing-Chiu;  Zhang,Quan-Wei;  Liu,Man;  Chen,Miao-Miao;  Wen,Xin;  Wu,Hoi-Yan;  Cheng,Hui-Yuan;  Puno,Pema-Tenzin;  Zhang,Ji-Xia;  Fung,Hau-Yee;  Bai,Su-Ping;  Wong,Tin-Long;  Zhao,Zhong-Zhen;  Cao,Hui;  Tsim,Karl Wah-Keung;  Shaw,Pang-Chui;  Han,Quan-Bin;  Sun,Han-Dong
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Cordyceps  Polysaccharide  Marker  Authentication  Immune activity  STRUCTURAL-ANALYSIS  SINENSIS  AUTHENTICATION  MACROPHAGES  SEQUENCE  
Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 203, 页码: 114200
Authors:  Zhou,Zi-Meng;  Yan,Dong-Mei;  Wang,Yi-Kun;  Zhang,Ting;  Xiao,Xue-Rong;  Dai,Man-Yun;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
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Raspberry  Q-markers  Quality evaluation  UPLC-ESI-QTOF-MS  COMPONENTS  ACTIVATION  PATHWAY  FRUITS  
A chromosome-scale Gastrodia elata genome and large-scale comparative genomic analysis indicate convergent evolution by gene loss in mycoheterotrophic and parasitic plants 期刊论文
PLANT JOURNAL, 2021, 卷号: 108, 期号: 6, 页码: 1609-1623
Authors:  Xu,Yuxing;  Lei,Yunting;  Su,Zhongxiang;  Zhao,Man;  Zhang,Jingxiong;  Shen,Guojing;  Wang,Lei;  Li,Jing;  Qi,Jinfeng;  Wu,Jianqiang
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Gastrodia elata  mycoheterotrophic plant  parasitic plant  gene loss  convergent evolution  BIOSYNTHESIS  VITAMIN-K-1  TRANSPORT  SYMBIOSIS  ACID