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A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
Favorite  |  View/Download:3/0  |  Submit date:2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
Favorite  |  View/Download:4/0  |  Submit date:2022/04/02
terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
Authors:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
Favorite  |  View/Download:5/0  |  Submit date:2022/04/02
cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
Immunostimulatory 6/6/6/6 Tetracyclic Triterpenoid Saponins with the Methyl-30 Incorporated Cyclization from the Root of Colquhounia elegans 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7462-7466
Authors:  Hua,Juan;  Liu,Yan-Chun;  Luo,Shi-Hong;  Liu,Yan;  Xiao,Chao-Jiang;  Li,Xiao-Nian;  Li,Sheng-Hong
Favorite  |  View/Download:2/0  |  Submit date:2022/04/02
QUILLAJA-SAPONARIA  BIOSYNTHESIS  MECHANISMS  ADJUVANTS  VARIANTS  PRODUCTS  CYCLASE  
Peltate glandular trichomes of Colquhounia vestita harbor diterpenoid acids that contribute to plant adaptation to UV radiation and cold stresses 期刊论文
PHYTOCHEMISTRY, 2020
Authors:  Tang, Ting;  Li, Chun-Huan;  Li, De-Sen;  Jing, Shu-Xi;  Hua, Juan;  Luo, Shi-Hong;  Liu, Yan;  Li, Sheng-Hong
View  |  Adobe PDF(2106Kb)  |  Favorite  |  View/Download:23/7  |  Submit date:2021/01/05
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2020
Authors:  Liu, Yan;  Luo, Shi-Hong;  Hua, Juan;  Li, De-Sen;  Ling, Yi;  Luo, Qian;  Li, Sheng-Hong
View  |  Adobe PDF(30959Kb)  |  Favorite  |  View/Download:7/5  |  Submit date:2021/01/05
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
Authors:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
View  |  Adobe PDF(1517Kb)  |  Favorite  |  View/Download:127/11  |  Submit date:2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 148, 页码: 57-62
Authors:  Zheng, Guowei;  Luo, Shihong;  Li, Shifei;  Hua, Juan;  Li, Weiqi;  Li, Shenghong
Favorite  |  View/Download:171/0  |  Submit date:2018/05/08
Ageratina Adenophora  Asteraceae  Roots  Specialized Metabolites  Antifungal Activity  
三种植物的次生代谢产物及其生物功能研究 学位论文
: 中国科学院大学, 2017
Authors:  华娟
Adobe PDF(9527Kb)  |  Favorite  |  View/Download:99/18  |  Submit date:2019/06/14
New Bioactive Macrocyclic Diterpenoids from Euphorbia helioscopia 期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 10, 页码: 1
Authors:  Hua, Juan;  Luo, Shi-Hong;  Liu, Yan;  Liu, Yan-Chun;  Tan, Yan-Yun;  Feng, Ling;  Xiao, Chao-Jiang;  Zhang, Ke-Qin;  Li, Sheng-Hong;  Niu, Xue-Mei
View  |  Adobe PDF(544Kb)  |  Favorite  |  View/Download:216/61  |  Submit date:2017/11/17
Euphorbia Helioscopia  Euphoscopoids a -c  Diterpenoids  Antifeedant Activities  Cytotoxic Activities.