Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi
Zheng, Guowei1,2; Luo, Shihong1,3; Li, Shifei4; Hua, Juan1; Li, Weiqi2; Li, Shenghong1
2018-04-01
Source PublicationPHYTOCHEMISTRY
ISSN0031-9422
Volume148Pages:57-62
AbstractThe Asteraceae plant Ageratina adenophora (also called Eupatorium adenophorum) has became the most destructive invasive species in China, especially the southwestern region, and is gravely threatening the native biodiversity. Its high reproductive capacity is partly due to the developed root system. From the roots of A. adenophora, ten compounds including three previously undescribed benzofuran derivatives (7-hydroxy-dehydrotremetone, 7,10,11-trihydroxy dehydrotremetone, 10-oxo-7-hydroxy-nordehydro-tremetone), a previously undescribed chromene derivative (5-beta-glucosyl-7-demethoxy-encecalin) and a previously undescribed monoterpene glucoside (8-hydroxy-8-beta-glucosy1-2-carene) were isolated and identified. The previously undescribed structures were established by spectroscopic studies including 1 D and 2D-NMR and HR-MS analyses. Antifungal activity of six compounds against one strain of pathogenic fungus of A. adenophora, Alternaria alternata, and other four strains of agricultural pathogenic fungi, Colletotrichum gloeosporioides, C. musae, Rhizoctonia solani and Fusarium oxysporum f. sp. niveum were investigated. The most abundant compound we isolated from A. adenophora roots was 7-hydroxy-dehydrotremetone, which showed significant broad-spectral inhibitory activity against the growth of all tested fungal strains, with diameter of inhibitory zones ranging from 13.90 +/- 1.05 mm to 17.28 +/- 0.46 mm at 50 mu g/disk (nystatin: 24.76 +/- 1.19 mm to 36.64 +/- 0.85 mm). Encecalin also showed weak inhibitory activity against F oxysporum f. sp. niveum, while other compounds were not active. Our results suggested that 7-hydroxy-dehydrotremetone might function as a constitutive defense compound in the roots of A. adenophora against pathogenic fungi. (C) 2018 Elsevier Ltd. All rights reserved.
KeywordAgeratina Adenophora Asteraceae Roots Specialized Metabolites Antifungal Activity
DOI10.1016/j.phytochem.2018.01.013
Language英语
WOS IDWOS:000427334600007
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/60524
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Germplasm Bank Wild Species, Kunming 650201, Yunnan, Peoples R China
3.Shenyang Agr Univ, Coll Biosci & Biotechnol, Shenyang 110866, Liaoning, Peoples R China
4.Shanxi Univ, Inst Mol Sci, Taiyuan 030006, Shanxi, Peoples R China
Recommended Citation
GB/T 7714
Zheng, Guowei,Luo, Shihong,Li, Shifei,et al. Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi[J]. PHYTOCHEMISTRY,2018,148:57-62.
APA Zheng, Guowei,Luo, Shihong,Li, Shifei,Hua, Juan,Li, Weiqi,&Li, Shenghong.(2018).Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi.PHYTOCHEMISTRY,148,57-62.
MLA Zheng, Guowei,et al."Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi".PHYTOCHEMISTRY 148(2018):57-62.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zheng, Guowei]'s Articles
[Luo, Shihong]'s Articles
[Li, Shifei]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zheng, Guowei]'s Articles
[Luo, Shihong]'s Articles
[Li, Shifei]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zheng, Guowei]'s Articles
[Luo, Shihong]'s Articles
[Li, Shifei]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.