Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi
Zheng, Guowei1,2; Luo, Shihong1,3; Li, Shifei4; Hua, Juan1; Li, Weiqi2; Li, Shenghong1
2018-04-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号148页码:57-62
摘要The Asteraceae plant Ageratina adenophora (also called Eupatorium adenophorum) has became the most destructive invasive species in China, especially the southwestern region, and is gravely threatening the native biodiversity. Its high reproductive capacity is partly due to the developed root system. From the roots of A. adenophora, ten compounds including three previously undescribed benzofuran derivatives (7-hydroxy-dehydrotremetone, 7,10,11-trihydroxy dehydrotremetone, 10-oxo-7-hydroxy-nordehydro-tremetone), a previously undescribed chromene derivative (5-beta-glucosyl-7-demethoxy-encecalin) and a previously undescribed monoterpene glucoside (8-hydroxy-8-beta-glucosy1-2-carene) were isolated and identified. The previously undescribed structures were established by spectroscopic studies including 1 D and 2D-NMR and HR-MS analyses. Antifungal activity of six compounds against one strain of pathogenic fungus of A. adenophora, Alternaria alternata, and other four strains of agricultural pathogenic fungi, Colletotrichum gloeosporioides, C. musae, Rhizoctonia solani and Fusarium oxysporum f. sp. niveum were investigated. The most abundant compound we isolated from A. adenophora roots was 7-hydroxy-dehydrotremetone, which showed significant broad-spectral inhibitory activity against the growth of all tested fungal strains, with diameter of inhibitory zones ranging from 13.90 +/- 1.05 mm to 17.28 +/- 0.46 mm at 50 mu g/disk (nystatin: 24.76 +/- 1.19 mm to 36.64 +/- 0.85 mm). Encecalin also showed weak inhibitory activity against F oxysporum f. sp. niveum, while other compounds were not active. Our results suggested that 7-hydroxy-dehydrotremetone might function as a constitutive defense compound in the roots of A. adenophora against pathogenic fungi. (C) 2018 Elsevier Ltd. All rights reserved.
关键词Ageratina Adenophora Asteraceae Roots Specialized Metabolites Antifungal Activity
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/60524
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Germplasm Bank Wild Species, Kunming 650201, Yunnan, Peoples R China
3.Shenyang Agr Univ, Coll Biosci & Biotechnol, Shenyang 110866, Liaoning, Peoples R China
4.Shanxi Univ, Inst Mol Sci, Taiyuan 030006, Shanxi, Peoples R China
推荐引用方式
GB/T 7714
Zheng, Guowei,Luo, Shihong,Li, Shifei,et al. Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi[J]. PHYTOCHEMISTRY,2018,148:57-62.
APA Zheng, Guowei,Luo, Shihong,Li, Shifei,Hua, Juan,Li, Weiqi,&Li, Shenghong.(2018).Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi.PHYTOCHEMISTRY,148,57-62.
MLA Zheng, Guowei,et al."Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi".PHYTOCHEMISTRY 148(2018):57-62.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zheng, Guowei]的文章
[Luo, Shihong]的文章
[Li, Shifei]的文章
百度学术
百度学术中相似的文章
[Zheng, Guowei]的文章
[Luo, Shihong]的文章
[Li, Shifei]的文章
必应学术
必应学术中相似的文章
[Zheng, Guowei]的文章
[Luo, Shihong]的文章
[Li, Shifei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。