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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
Authors:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
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DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Silvaticusins A-D: ent-kaurane diterpenoids and a cyclobutane-containing ent-kaurane dimer from Isodon silvaticus. 期刊论文
Natural products and bioprospecting, 2024, 卷号: 14, 期号: 1, 页码: 45-45
Authors:  Hai, Qi-Xiu;  Hu, Kun;  Chen, Su-Ping;  Fu, Yang-Yang;  Li, Xiao-Nian;  Sun, Han-Dong;  He, Hong-Ping;  Puno, Pema-Tenzin
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Recent advances in the application of [2+2] cycloaddition in the chemical synthesis of cyclobutane-containing natural products. 期刊论文
Natural products and bioprospecting, 2024, 卷号: 14, 期号: 1, 页码: 37-37
Authors:  Hou, Song-Yu;  Yan, Bing-Chao;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
Authors:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
View  |  Adobe PDF(7289Kb)  |  Favorite  |  View/Download：749/356  |  Submit date：2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Four new lanostane triterpenoids featuring extended pi-conjugated systems from the stems of Kadsura coccinea. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 12-12
Authors:  Zhang, Qi-Qi;  Hu, Kun;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
Authors:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
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Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Tangutidines A-C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 4, 页码: 459-464
Authors:  Li,Hao-Yi;  Yan,Bing-Chao;  Wei,Li-Xin;  Sun,Han-Dong;  Puno,Pema-Tenzin
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A specific and bioactive polysaccharide marker for Cordyceps 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343
Authors:  Li,Li-Feng;  But,Grace Wing-Chiu;  Zhang,Quan-Wei;  Liu,Man;  Chen,Miao-Miao;  Wen,Xin;  Wu,Hoi-Yan;  Cheng,Hui-Yuan;  Puno,Pema-Tenzin;  Zhang,Ji-Xia;  Fung,Hau-Yee;  Bai,Su-Ping;  Wong,Tin-Long;  Zhao,Zhong-Zhen;  Cao,Hui;  Tsim,Karl Wah-Keung;  Shaw,Pang-Chui;  Han,Quan-Bin;  Sun,Han-Dong
View  |  Adobe PDF(3527Kb)  |  Favorite  |  View/Download：736/378  |  Submit date：2022/04/02
Cordyceps  Polysaccharide  Marker  Authentication  Immune activity  STRUCTURAL-ANALYSIS  SINENSIS  AUTHENTICATION  MACROPHAGES  SEQUENCE  
Chaetolactam A, an Azaphilone Derivative from the Endophytic Fungus Chaetomium sp. g1 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 1, 页码: 475-483
Authors:  Zu,Wen-Yu;  Tang,Jian-Wei;  Hu,Kun;  Zhou,Yuan-Fei;  Gou,Lei-Lei;  Su,Xiao-Zheng;  Lei,Xinxiang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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MASS-SPECTROMETRY  A-D  CASPASE-3  H-1  
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
Authors:  Li,Xing-Ren;  Yan,Bing-Chao;  Hu,Kun;  He,Shijun;  Sun,Han-Dong;  Zuo,Jianping;  Puno,Pema-Tenzin
View  |  Adobe PDF(1474Kb)  |  Favorite  |  View/Download：351/57  |  Submit date：2022/04/02
DIELS-ALDER REACTIONS  SENSITIZED PHOTOOXYGENATION  NATURAL-PRODUCTS  ACID  DITERPENOIDS