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USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 562, 页码: 21-28
作者:  Zhang,Shaohua;  Ju,Xiaoman;  Yang,Qihong;  Zhu,Yiying;  Fan,Dongmei;  Su,Guifeng;  Kong,Lingmei;  Li,Yan
浏览  |  Adobe PDF(2615Kb)  |  收藏  |  浏览/下载：140/36  |  提交时间：2022/04/02
USP47  Cancer stem cell  Colorectal cancer  Parthenolide  Deubiquitinase  SESQUITERPENE LACTONE PARTHENOLIDE  DEUBIQUITINASES  STABILIZATION  LEUKEMIA  
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：202/50  |  提交时间：2020/03/18
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：176/31  |  提交时间：2019/10/14
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
作者:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
浏览  |  Adobe PDF(5225Kb)  |  收藏  |  浏览/下载：236/27  |  提交时间：2019/06/24
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3911-3914
作者:  Wang, Li;  Yang, Jing;  Kong, Ling-Mei;  Deng, Jun;  Xiong, Zijun;  Huang, Jianping;  Luo, Jianping;  Yan, Yijun;  Hu, Yikao;  Li, Xiao-Nian;  Li, Yan;  Zhao, Yong;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1338Kb)  |  收藏  |  浏览/下载：274/76  |  提交时间：2017/10/23
Protein-kinase-c  Phorbol Esters  Biological Evaluation  Biosynthesis  (+)-phorbol  Analogs  Cancer  Seeds  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：172/36  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：274/70  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 20, 页码: 10140-10150
作者:  Zhou, Hongyu;  Shen, Tao;  Shang, Chaowei;  Luo, Yan;  Liu, Lei;  Yan, Juming;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(2703Kb)  |  收藏  |  浏览/下载：209/45  |  提交时间：2015/06/17
Ciclopirox  Autophagy  Rhabdomyosarcoma  Reactive Oxygen Species  Jnk  
Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 3, 页码: 1599-1611
作者:  Wan, Wei-Chao;  Chen, Wen;  Liu, Lan-Xiang;  Li, Yan;  Yang, Li-Juan;  Deng, Xiao-Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(509Kb)  |  收藏  |  浏览/下载：783/524  |  提交时间：2014/04/09
Hybrid Compound  Benzofuran  Imidazole  Cytotoxic Activity  Structure-activity Relationships  Molecular Docking  
Scapiformolactones A-I: Germacrane sesquiterpenoids with an unusual Delta(3)-15,6-lactone moiety from Salvia scapiformis 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 96, 页码: 378-388
作者:  Lai, Yongji;  Xue, Yongbo;  Zhang, Mengke;  Zhang, Jinwen;  Tang, Wei;  Liu, Junjun;  Lei, Liang;  Yan, Juming;  Luo, Zengwei;  Zuo, Jianping;  Li, Yan;  Yao, Guangmin;  Zhang, Yonghui
浏览  |  Adobe PDF(1398Kb)  |  收藏  |  浏览/下载：238/47  |  提交时间：2015/05/12
Salvia Scapiformis  Lamiaceae  Germacrane Sesquiterpene  Conformation  Chemical Transformation  Quantum Mechanical Calculation  Cytotoxicity Immunomodulatory Activity