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New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
浏览  |  Adobe PDF(5266Kb)  |  收藏  |  浏览/下载：38/12  |  提交时间：2024/05/09
Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 16196
作者:  Cai,Min;  Bai,Xiao-Lin;  Zang,Hao-Jing;  Tang,Xiao-Han;  Yan,Ying;  Wan,Jia-Jia;  Peng,Min-You;  Liang,Hong;  Liu,Lin;  Guo,Feng;  Zhao,Pei-Ji;  Liao,Xun;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2612Kb)  |  收藏  |  浏览/下载：34/6  |  提交时间：2024/05/09
Harrisonia perforata  quassinoid  simarubaceae  neuroprotection  PC12 cells  PINK1(B9) flies  PROMISING BIOLOGICAL-ACTIVITY  UNPRECEDENTED QUASSINOIDS  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
浏览  |  Adobe PDF(11343Kb)  |  收藏  |  浏览/下载：36/9  |  提交时间：2024/05/09
euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS  
Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1541-1545
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Sun,Mao;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1835Kb)  |  收藏  |  浏览/下载：94/20  |  提交时间：2022/04/02
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu,Shuai;  Zhang,Cui-Shan;  Ran,Xiao-Qian;  Tang,Xiao-Han;  Guo,Ya-Rong;  Yan,Ying;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rong-Can;  Di,Ying-Tong
浏览  |  Adobe PDF(997Kb)  |  收藏  |  浏览/下载：116/37  |  提交时间：2022/04/02
PROMISING BIOLOGICAL-ACTIVITY  LIMONOIDS  CHROMONES  FRUITS  DRUG  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：165/56  |  提交时间：2023/09/08
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 3, 页码: 357-364
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Lu,Qing-Yun;  Liu,Shuai;  Li,Ying-Yao;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1584Kb)  |  收藏  |  浏览/下载：129/27  |  提交时间：2022/04/02
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：112/30  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：72/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
浏览  |  Adobe PDF(2105Kb)  |  收藏  |  浏览/下载：118/48  |  提交时间：2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA