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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载：185/0  |  提交时间：2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：174/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 44, 页码: 9605-9614
作者:  Liu, Bin;  Hou, Yan;  Wang, Xiaozheng;  Ma, Xiaofang;  Fang, Shiqi;  Huang, Tao;  Chen, Yanli;  Bai, Zhiqiang;  Lin, Shuangjun;  Zhang, Rundong;  Hu, Kaifeng
浏览  |  Adobe PDF(2826Kb)  |  收藏  |  浏览/下载：176/35  |  提交时间：2020/03/18
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：328/43  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Phlegmadine A: A Lycopodium Alkaloid with a Unique Cyclobutane Ring from Phlegmariurus phlegmaria 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 17, 页码: 11301-11305
作者:  Zhang, Zhi-Jun;  Wang, Chen;  Wu, Xing-De;  Huang, Yan;  Zhou, Wen-Xia;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1540Kb)  |  收藏  |  浏览/下载：182/20  |  提交时间：2019/11/07
Identification of novel monoamine oxidase selective inhibitors employing a hierarchical ligand-based virtual screening strategy 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 8, 页码: 801-816
作者:  Wang, Dong;  Li, Zhaoyang;  Liu, Yi;  Chen, Mo;  Chen, Nianhang;  Zuo, Zhili;  Kong, De-Xin
浏览  |  Adobe PDF(1462Kb)  |  收藏  |  浏览/下载：160/31  |  提交时间：2019/09/10
BRS-3D  monoamine oxidase selective inhibitors  virtual screening  
Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L. 期刊论文
FITOTERAPIA, 2019, 卷号: 134, 页码: 443-446
作者:  Jing, Chen-xu;  Guo, Jing-jing;  Yang, Bi-juan;  Fan, Shi-rui;  Wang, Yi-ting;  Chen, Duo-zhi;  Hao, Xiao-jiang
浏览  |  Adobe PDF(593Kb)  |  收藏  |  浏览/下载：236/36  |  提交时间：2019/07/29
Sesquiterpenoids  Stellera chamaejasme L.  Stelleraguaianone  Single-crystal X-ray  Cytotoxicity  A549 cells  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：315/38  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Three new Lycopodium alkaloids from Lycopodium japonicum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 1, 页码: 17-24
作者:  Zhu, Yu;  Dong, Liao-Bin;  Zhang, Zhi-Jun;  Fan, Min;  Zhu, Qin-Feng;  Qi, Yan-Yan;  Liu, Yu-Chen;  Peng, Li-Yan;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1103Kb)  |  收藏  |  浏览/下载：236/56  |  提交时间：2019/05/24
Lycopodiaceae  Lycopodium japonicum  Lycopodium alkaloids  T-type calcium channel  
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities 期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 265-271
作者:  Xu, Hong-Bo;  Yang, Tong-Hua;  Xie, Pei;  Tang, Zhi-Shu;  Song, Xiao;  Xu, Huai-Li;  Li, Yan-Hong;  Zhang, Dong-Bo;  Liu, Yan-Ru;  Liang, Yan-Ni;  Zhang, Yu;  Liu, Shi-Jun;  Wei, Si-Min;  Sun, Chen;  Liu, Hong-Bo;  Deng, Chong;  Wang, Wei
收藏  |  浏览/下载：228/0  |  提交时间：2018/12/03
Acanthopanax gracilistylus  Eudesmane-type sesquiterpenoid  LC-MS  Anti-inflammation  Anti-oxidant  Xanthine oxidase