Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L.
Jing, Chen-xu1; Guo, Jing-jing2; Yang, Bi-juan2; Fan, Shi-rui2; Wang, Yi-ting2; Chen, Duo-zhi2; Hao, Xiao-jiang2
Corresponding AuthorChen, Duo-zhi(chenduozhi@mail.kib.ac.cn) ; Hao, Xiao-jiang(haoxj@mail.kib.ac.cn)
2019-04-01
Source PublicationFITOTERAPIA
ISSN0367-326X
Volume134Pages:443-446
AbstractTwo new sesquiterpenoids were isolated from Stellera chamaejasme L., known as the traditional Chinese herb 'Rui Xiang Lang Du'. The compounds were elucidated as stelleraguaianone B (1) and C (2) by comprehensive spectroscopic analysis, including 1D and 2D NMR as well as HRESIMS, and by comparing their NMR data with known compounds. In addition, the structure of 1 was further confirmed by single-crystal X-ray diffraction analysis. Both the compounds were evaluated for their cytotoxicity on common tumour cell lines in vitro, which revealed that compound 1 exhibits cytotoxic activity on A549 cells, while 2 has no activity.
KeywordSesquiterpenoids Stellera chamaejasme L. Stelleraguaianone Single-crystal X-ray Cytotoxicity A549 cells
DOI10.1016/j.fitote.2019.03.024
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000468710300055
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/67549
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorChen, Duo-zhi; Hao, Xiao-jiang
Affiliation1.Changchun Univ Chinese Med, Affiliated Hosp, Res Ctr Tradit Chinese Med, Changchun 130021, Jilin, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Jing, Chen-xu,Guo, Jing-jing,Yang, Bi-juan,et al. Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L.[J]. FITOTERAPIA,2019,134:443-446.
APA Jing, Chen-xu.,Guo, Jing-jing.,Yang, Bi-juan.,Fan, Shi-rui.,Wang, Yi-ting.,...&Hao, Xiao-jiang.(2019).Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L..FITOTERAPIA,134,443-446.
MLA Jing, Chen-xu,et al."Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L.".FITOTERAPIA 134(2019):443-446.
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