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Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 121-128
作者:  Luo, Fei;  Ling, Yi;  Li, De-Sen;  Tang, Ting;  Liu, Yan-Chun;  Liu, Yan;  Li, Sheng-Hong
浏览  |  Adobe PDF(2851Kb)  |  收藏  |  浏览/下载：207/36  |  提交时间：2019/07/29
Leucosceptrum canum  Lamiaceae  Cedrol  Sesquiterpene cylase  Cedrol synthase  Heterologous production  Synthetic biology  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1093Kb)  |  收藏  |  浏览/下载：200/49  |  提交时间：2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2019, 卷号: 36, 期号: 4, 页码: 626-665
作者:  Liu, Yan;  Jing, Shu-Xi;  Luo, Shi-Hong;  Li, Sheng-Hong
浏览  |  Adobe PDF(5702Kb)  |  收藏  |  浏览/下载：214/35  |  提交时间：2019/05/24
Difengpienols A and B, two new sesqui-neolignans with anti-inflammatory activity from the bark of Illicium difengpi 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 30, 页码: 210-214
作者:  Pan, Zheng-Hong;  Cheng, Ling;  Ning, De-Sheng;  Peng, Li-Yan;  Fu, Yu-Xia;  Li, Lian-Chun
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Illicium difengpi  Difengpienol A  Difengpienol B  Sesqui-neolignans  Anti-inflammatory  
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
作者:  Ding, Lin-Fen;  Su, Jia;  Pan, Zheng-Hong;  Zhang, Zhi-Jun;  Li, Xiao-Nian;  Song, Liu-Dong;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载：577/144  |  提交时间：2018/11/12
Magnolia Grandiflora (Magnoliaceae)  Sesquiterpenoids  Cytotoxic Activity  Nf-kappa b Transcriptional Activity  
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：411/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Localisation of Two Bioactive Labdane Diterpenoids in the Peltate Glandular Trichomes of Leonurus japonicus by Laser Microdissection Coupled with UPLC-MS/MS 期刊论文
PHYTOCHEMICAL ANALYSIS, 2017, 卷号: 28, 期号: 5, 页码: 404-409
作者:  Xiao, Chao-Jiang;  Liu, Yan-Chun;  Luo, Shi-Hong;  Hua, Juan;  Liu, Yan;  Li, Sheng-Hong
浏览  |  Adobe PDF(282Kb)  |  收藏  |  浏览/下载：234/72  |  提交时间：2017/10/23
Leonurus Japonicus  Glandular Trichomes  Laser Microdissection  Labdane Diterpenoids  Biological Activities  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：178/37  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 20, 页码: 10140-10150
作者:  Zhou, Hongyu;  Shen, Tao;  Shang, Chaowei;  Luo, Yan;  Liu, Lei;  Yan, Juming;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(2703Kb)  |  收藏  |  浏览/下载：215/46  |  提交时间：2015/06/17
Ciclopirox  Autophagy  Rhabdomyosarcoma  Reactive Oxygen Species  Jnk  
Eriocalyxin B-Induced Apoptosis in Pancreatic Adenocarcinoma Cells Through Thiol-Containing Antioxidant Systems and Downstream Signalling Pathways 期刊论文
CURRENT MOLECULAR MEDICINE, 2014, 卷号: 14, 期号: 5, 页码: 673-689
作者:  Li, L.;  Yue, G. G. L.;  Pu, J. X.;  Sun, H. D.;  Fung, K. P.;  Leung, P. C.;  Han, Q. B.;  Lau, C. B. S.;  Leung, P. S.;  Xu, JC (reprint author), Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Biodivers & Biogeog East Asia, Kunming 650201, Yunnan, Peoples R China.;  j.c.xu@cgiar.org;  kdhyde3@gmail.com
浏览  |  Adobe PDF(998Kb)  |  收藏  |  浏览/下载：270/94  |  提交时间：2014/10/11
Apoptosis  Eriocalyxin b  Pancreatic Cancer  Reactive Oxygen Species  Thiols