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Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：278/42  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：188/39  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
浏览  |  Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：806/151  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Synthesis and antitumor activity of novel N-substituted tetrahydro-beta-carboline-imidazolium salt derivatives 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 39, 页码: 9423-9430
作者:  Zhou, Bei;  Liu, Zheng-Fen;  Deng, Guo-Gang;  Chen, Wen;  Li, Min-Yan;  Yang, Li-Juan;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hong-Bin
浏览  |  Adobe PDF(5636Kb)  |  收藏  |  浏览/下载：204/40  |  提交时间：2016/12/21
Novel beta-carbolines inhibit Wnt/beta-catenin signaling 期刊论文
CELL DEATH & DISEASE, 2015, 卷号: 6, 期号: 11, 页码: e1983
作者:  Kong, LM;  Mao, BY;  Zhu, HJ;  Li, Y.
浏览  |  Adobe PDF(232Kb)  |  收藏  |  浏览/下载：236/70  |  提交时间：2016/02/01
Syntheses of novel beta-carboline derivatives and the activities against five tumor-cell lines 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 1, 页码: 96-98
作者:  Bai, Bing;  Li, Xing-Yao;  Liu, Li;  Li, Yan;  Zhu, Hua-Jie
浏览  |  Adobe PDF(299Kb)  |  收藏  |  浏览/下载：233/62  |  提交时间：2014/04/09
Beta-carbolines  Cytotoxic Activity  Structure-activity Relationship  Mtt  
beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 6, 页码: 2296-2299
作者:  Li, Shi-Fei;  Zhang, Yu;  Li, Yan;  Li, Xin-Rao;  Kong, Ling-Mei;  Tan, Cheng-Jian;  Li, Shun-Lin;  Di, Ying-Tong;  He, Hong-Ping;  Hao, Xiao-Jiang
Adobe PDF(228Kb)  |  收藏  |  浏览/下载：531/187  |  提交时间：2012/06/07
Trigonostemon Lii  Beta-carboline Alkaloids  Trigonostemines A-f  Cytotoxic Activity  
Design, synthesis and cytotoxic activities of novel beta-amino alcohol derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 卷号: 21, 期号: 8, 页码: 2302-2304
作者:  Bai, Bing;  Li, Xing-Yao;  Li, Yan;  Zhu, Hua-Jie
Adobe PDF(209Kb)  |  收藏  |  浏览/下载：292/118  |  提交时间：2012/04/10
Beta-amino Alcohol  Cytotoxic Activity  Structure-activity Relationship  Mtt